Stiffness Is the Cardinal Symptom of Inflammatory Musculoskeletal Diseases, Yet Still Variably Measured: Report from the OMERACT 2016 Stiffness Special Interest Group

Serena Halls*, Premarani Sinnathurai, Sarah Hewlett, Sarah L. Mackie, Lyn March, Susan J. Bartlett, Clifton O. Bingham, Rieke Alten, Ina Campbell, Catherine L. Hill, Robert J. Holt, Rod Hughes, John R. Kirwan, Amye L. Leong, Ying Ying Leung, Anne Lyddiatt, Lorna Neill, Ana Maria Orbai

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

10 Citations (Scopus)

Abstract

OBJECTIVE: The objectives of the Outcome Measures in Rheumatology (OMERACT) Stiffness special interest group (SIG) are to characterize stiffness as an outcome in rheumatic disease and to identify and validate a stiffness patient-reported outcome (PRO) in rheumatology.

METHODS: At OMERACT 2016, international groups presented and discussed results of several concurrent research projects on stiffness: a literature review of rheumatoid arthritis (RA) stiffness PRO measures, a qualitative investigation into the RA and polymyalgia rheumatica patient perspective of stiffness, data-driven stiffness conceptual model development, development and testing of an RA stiffness PRO measure, and a quantitative work testing stiffness items in patients with RA and psoriatic arthritis.

RESULTS: The literature review identified 52 individual stiffness PRO measures assessing morning or early morning stiffness severity/intensity or duration. Items were heterogeneous, had little or inconsistent psychometric property evidence, and did not appear to have been developed according to the PRO development guidelines. A poor match between current stiffness PRO and the conceptual model identifying the RA patient experience of stiffness was identified, highlighting a major flaw in PRO selection according to the OMERACT filter 2.0.

CONCLUSION: Discussions within the Stiffness SIG highlighted the importance of further research on stiffness and defined a research agenda.

Original languageEnglish
Pages (from-to)1904-1910
Number of pages7
JournalJournal of Rheumatology
Volume44
Issue number12
Early online date15 Dec 2016
DOIs
Publication statusPublished - 1 Dec 2017

Keywords

  • Omeract
  • Outcome measurement
  • Stiffness

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