Structural synaptic plasticity across sleep and wake

Michele Bellesi, Luisa de Vivo

Research output: Contribution to journalReview article (Academic Journal)peer-review

8 Citations (Scopus)
131 Downloads (Pure)


Sleep-dependent synaptic plasticity is crucial for optimal cognition. However, establishing the direction of synaptic plasticity during sleep has been particularly challenging since data in support of both synaptic potentiation and depotentiation have been reported. This review focuses on structural synaptic plasticity across sleep and wake and summarizes recent developments in the use of 3-dimensional electron microscopy as applied to this field.
Original languageEnglish
Pages (from-to)74-81
Number of pages8
JournalCurrent Opinion in Physiology
Early online date23 Dec 2019
Publication statusPublished - 1 Jun 2020


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