Substrate specificity of strictosidine synthase

E McCoy, MC Galan , SE O'Connor

Research output: Contribution to journalArticle (Academic Journal)peer-review

78 Citations (Scopus)


Strictosidine synthase catalyzes a Pictet–Spengler reaction in the first step in the biosynthesis of terpene indole alkaloids to generate strictosidine. The substrate requirements for strictosidine synthase are systematically and quantitatively examined and the enzymatically generated compounds are processed by the second enzyme in this biosynthetic pathway.
Translated title of the contributionSubstrate specificity of strictosidine synthase
Original languageEnglish
Pages (from-to)2475 - 2478
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume16 (9)
Publication statusPublished - May 2006

Bibliographical note

Publisher: Elsevier


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