Subtleties in asymmetric catalyst structure: the resolution of a 6-phospha-2,4,8-trioxa-adamantane and its applications in asymmetric hydrogenation catalysis

Jonathan Hopewell, Piotr Jankowski, Claire L. McMullin, A. Guy Orpen, Paul G. Pringle

Research output: Contribution to journalArticle (Academic Journal)peer-review

19 Citations (Scopus)

Abstract

An efficient, classical resolution of the versatile P-ligand intermediate 6-phospha-2,4,8-trioxa-adamantane (CgPH) is described and the rhodium complex of the optically pure secondary phosphine beta-CgPH is an active and moderately selective asymmetric hydrogenation catalyst.

Original languageEnglish
Pages (from-to)100-102
Number of pages3
JournalChemical Communications
Volume46
Issue number1
DOIs
Publication statusPublished - 2010

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