Surrogate end points in cardio-thoracic trials: a call for better reporting and improved interpretation of trial findings

Oriana Ciani*, Anthony Muchai Manyara, Rod S Taylor

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

2 Citations (Scopus)

Abstract

Evidence to inform regulatory, funding and clinical decisions about health interventions should come from well-conducted clinical trials. Despite the challenges associated to their design, conduct and generalizability, randomized controlled trials (RCTs) are typically considered the studies providing the least biased estimates of treatment effects
Original languageEnglish
Article numberezac449
Number of pages4
JournalEuropean Journal of Cardio-Thoracic Surgery
Volume62
Issue number4
Early online date16 Sept 2022
DOIs
Publication statusPublished - 1 Oct 2022

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