Sympathetic neural regulation of blood pressure: influences of sex and aging

E C J Hart, N Charkoudian

Research output: Contribution to journalArticle (Academic Journal)peer-review

100 Citations (Scopus)


Sex and age have important influences on sympathetic neural control of blood pressure in humans. Young women are relatively protected against risk of hypertension due to greater peripheral vasodilator influences compared with young men and older people. This protective effect is lost at menopause. Older men and women have higher sympathetic nerve activity and tighter coupling between SNA and blood pressure, contributing to the increased risk of hypertension with aging.

Original languageEnglish
Pages (from-to)8-15
Number of pages8
JournalPhysiology (Bethesda, Md.)
Issue number1
Publication statusPublished - Jan 2014


  • Aging
  • Animals
  • Blood Pressure
  • Hemodynamics
  • Humans
  • Sex Characteristics
  • Sympathetic Nervous System


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