Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Tiddo J. Mooibroek; Matthew P. Crump; Anthony Davis

doi:10.1039/c6ob00023a

Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Tiddo J. Mooibroek, Matthew P. Crump, Anthony Davis

Research output: Contribution to journal › Article (Academic Journal) › peer-review

22 Citations (Scopus)

334 Downloads (Pure)

Abstract

A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

Original language	English
Pages (from-to)	1930-1933
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	14
Issue number	6
DOIs	https://doi.org/10.1039/c6ob00023a
Publication status	Published - 14 Jan 2016

Research Groups and Themes

Bristol BioDesign Institute

Keywords

synthetic biology

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10.1039/c6ob00023a

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This is the final published version of the article (version of record). It first appeared online via Royal Society of Chemistry at DOI: 10.1039/c6ob00023a. Please refer to any applicable terms of use of the publisher.
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A 13C NMR Coldprobe to Underpin Chemistry Research.
Butts, C. P. (Principal Investigator)
28/02/14 → 29/11/17
Project: Research
3-month Core Capability for Chemistry Research
Crosby, J. (Principal Investigator)
1/01/13 → 1/04/13
Project: Research
From "temples" to "courtyards" for carbohydrate recognition - expanding the scope of synthetic lectins.
Davis, A. P. (Principal Investigator)
1/10/11 → 1/10/14
Project: Research

Cite this

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title = "Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility",

abstract = "A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.",

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author = "Mooibroek, {Tiddo J.} and Crump, {Matthew P.} and Anthony Davis",

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AB - A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

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U2 - 10.1039/c6ob00023a

DO - 10.1039/c6ob00023a

M3 - Article (Academic Journal)

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Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Abstract

Research Groups and Themes

Keywords

Access to Document

Handle.net

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Projects

A 13C NMR Coldprobe to Underpin Chemistry Research.

3-month Core Capability for Chemistry Research

From "temples" to "courtyards" for carbohydrate recognition - expanding the scope of synthetic lectins.

Cite this