Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Tiddo J. Mooibroek; Matthew P. Crump; Anthony Davis

doi:10.1039/c6ob00023a

Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Tiddo J. Mooibroek, Matthew P. Crump, Anthony Davis

Research output: Contribution to journal › Article (Academic Journal) › peer-review

14 Citations (Scopus)

230 Downloads (Pure)

Abstract

A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

Original language	English
Pages (from-to)	1930-1933
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	14
Issue number	6
DOIs	https://doi.org/10.1039/c6ob00023a
Publication status	Published - 14 Jan 2016

Access to Document

10.1039/c6ob00023a

Full-text PDF (final published version)
This is the final published version of the article (version of record). It first appeared online via Royal Society of Chemistry at DOI: 10.1039/c6ob00023a. Please refer to any applicable terms of use of the publisher.
Final published version, 1.05 MB

4 Finished

A 13C NMR Coldprobe to Underpin Chemistry Research.
Butts, C. P.
28/02/14 → 29/11/17
Project: Research
3-month Core Capability for Chemistry Research
Crosby, J.
1/01/13 → 1/04/13
Project: Research
From "temples" to "courtyards" for carbohydrate recognition - expanding the scope of synthetic lectins.
Davis, A. P.
1/10/11 → 1/10/14
Project: Research

Cite this

@article{ec733eae36594663a2fc9e24336823cf,

title = "Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility",

abstract = "A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.",

author = "Mooibroek, {Tiddo J.} and Crump, {Matthew P.} and Anthony Davis",

year = "2016",

month = jan,

day = "14",

doi = "10.1039/c6ob00023a",

language = "English",

volume = "14",

pages = "1930--1933",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "6",

}

TY - JOUR

T1 - Synthesis and evaluation of a desymmetrised synthetic lectin

T2 - An approach to carbohydrate receptors with improved versatility

AU - Mooibroek, Tiddo J.

AU - Crump, Matthew P.

AU - Davis, Anthony

PY - 2016/1/14

Y1 - 2016/1/14

N2 - A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

AB - A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M-1 are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

U2 - 10.1039/c6ob00023a

DO - 10.1039/c6ob00023a

M3 - Article (Academic Journal)

C2 - 26786502

VL - 14

SP - 1930

EP - 1933

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 6

ER -

Synthesis and evaluation of a desymmetrised synthetic lectin: An approach to carbohydrate receptors with improved versatility

Abstract

Access to Document

Fingerprint

Projects

A 13C NMR Coldprobe to Underpin Chemistry Research.

3-month Core Capability for Chemistry Research

From "temples" to "courtyards" for carbohydrate recognition - expanding the scope of synthetic lectins.

Cite this