Synthesis, Anti-Inflammatory, and Analgesic Evaluation of Some 2-Amino-5-Selenothiazoles

Moustafa A. Gouda; Yousery El Sayed Sherif; Mohamed Elsherbini

doi:10.1080/10426507.2014.884091

Synthesis, Anti-Inflammatory, and Analgesic Evaluation of Some 2-Amino-5-Selenothiazoles

Moustafa A. Gouda
, Yousery El Sayed Sherif
, Mohamed Elsherbini

School of Chemistry

Research output: Contribution to journal › Article (Academic Journal) › peer-review

43 Citations (Scopus)

Abstract

Treatment of 2-aminothiazole (1) with triselenium dicyanide (2) afforded selenocyanate (3). Reduction of 3 with NaBH₄ gave the diselenide 4. Compounds 3 and 4 were used as a key intermediate for the synthesis of a series of 2-amino-5-selenothiazoles. The newly synthesized compounds were evaluated as anti-inflammatory and analgesic agent.

Original language	English
Journal	Phosphorus, Sulfur and Silicon and the Related Elements
DOIs	https://doi.org/10.1080/10426507.2014.884091
Publication status	Published - 2 Nov 2014

Access to Document

10.1080/10426507.2014.884091

Handle.net

Persistent link

Cite this

@article{8a80b471f7e841b59569b6c8cddc87ef,

title = "Synthesis, Anti-Inflammatory, and Analgesic Evaluation of Some 2-Amino-5-Selenothiazoles",

abstract = "Treatment of 2-aminothiazole (1) with triselenium dicyanide (2) afforded selenocyanate (3). Reduction of 3 with NaBH4 gave the diselenide 4. Compounds 3 and 4 were used as a key intermediate for the synthesis of a series of 2-amino-5-selenothiazoles. The newly synthesized compounds were evaluated as anti-inflammatory and analgesic agent.",

author = "Gouda, \{Moustafa A.\} and Sherif, \{Yousery El Sayed\} and Mohamed Elsherbini",

year = "2014",

month = nov,

day = "2",

doi = "10.1080/10426507.2014.884091",

language = "English",

journal = "Phosphorus, Sulfur and Silicon and the Related Elements",

issn = "1563-5325",

publisher = "Taylor \& Francis Group",

}

TY - JOUR

T1 - Synthesis, Anti-Inflammatory, and Analgesic Evaluation of Some 2-Amino-5-Selenothiazoles

AU - Gouda, Moustafa A.

AU - Sherif, Yousery El Sayed

AU - Elsherbini, Mohamed

PY - 2014/11/2

Y1 - 2014/11/2

N2 - Treatment of 2-aminothiazole (1) with triselenium dicyanide (2) afforded selenocyanate (3). Reduction of 3 with NaBH4 gave the diselenide 4. Compounds 3 and 4 were used as a key intermediate for the synthesis of a series of 2-amino-5-selenothiazoles. The newly synthesized compounds were evaluated as anti-inflammatory and analgesic agent.

AB - Treatment of 2-aminothiazole (1) with triselenium dicyanide (2) afforded selenocyanate (3). Reduction of 3 with NaBH4 gave the diselenide 4. Compounds 3 and 4 were used as a key intermediate for the synthesis of a series of 2-amino-5-selenothiazoles. The newly synthesized compounds were evaluated as anti-inflammatory and analgesic agent.

UR - https://pure.hud.ac.uk/en/publications/5db320d5-e29b-4d35-8c23-7625783ff9c4

U2 - 10.1080/10426507.2014.884091

DO - 10.1080/10426507.2014.884091

M3 - Article (Academic Journal)

SN - 1563-5325

JO - Phosphorus, Sulfur and Silicon and the Related Elements

JF - Phosphorus, Sulfur and Silicon and the Related Elements

ER -

Synthesis, Anti-Inflammatory, and Analgesic Evaluation of Some 2-Amino-5-Selenothiazoles

Abstract

Access to Document

Handle.net

Other files and links

Fingerprint

Cite this