Synthesis of Hetero-Polymer Functionalized Nanocarriers by Combining Surface-Initiated ATRP and RAFT Polymerization

Xin Huang, Nicole Hauptmann, Dietmar Appelhans, Petr Formanek, Simon Frank, Stefan Kaskel, Achim Temme, Brigitte Voit

Research output: Contribution to journalArticle (Academic Journal)peer-review

37 Citations (Scopus)

Abstract

Smart nanocarriers are created based on a bi-functional hetero-initiator for RAFT and ATRP technique, bi-functionalizing mesoporous silica nanoparticles with two polymer types. The pH-dependent behavior of PDEAEMA as the gatekeeper polymer is verified by electrokinetic measurements and a controlled release behavior is demonstrated using doxorubicin as the drug.
Original languageEnglish
Pages (from-to)3579-3583
JournalSmall
Volume8
Issue number23
DOIs
Publication statusPublished - 7 Dec 2012

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