SYNTHESIS OF ISOTOPICALLY LABELED 3-AMINO-2-PHENYLPROPIONIC ACID AND ITS ROLE AS A PRECURSOR IN THE BIOSYNTHESIS OF TENELLIN AND TROPIC ACID

RJ COX, D OHAGAN, Russell J Cox

Research output: Contribution to journalArticle (Academic Journal)

Abstract

A synthesis of [3-C-13]- and [3-C-14]-3-amino-2-phenylpropionic acids 7a and 7b is described. The incorporation of this amino acid into tenellin 1 from Beauveria bassiana (Bals.) Vuill. and into tropic acid 10 moiety of the tropane alkaloids hyscoyamine 8 and scopolamine 9 from Datura innoxia was studied but proved unsuccessful in each case.

Original languageEnglish
Pages (from-to)2537-2540
Number of pages4
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number10
Publication statusPublished - Oct 1991

Keywords

  • TROPANE ALKALOIDS
  • PHENYLALANINE
  • REARRANGEMENT
  • 1,2-MIGRATION
  • CHEMISTRY
  • C-13

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