Synthesis of Mono- and Diaza-'Pyridones' via Stille Coupling of Alkoxystannanes

Charlotte L. Smith; Christoph Hirschhaeuser; Georgia K. Malcolm; Daniel J. Nasrallah; Timothy Gallagher

doi:10.1055/s-0034-1378331

Synthesis of Mono- and Diaza-'Pyridones' via Stille Coupling of Alkoxystannanes

Charlotte L. Smith, Christoph Hirschhaeuser, Georgia K. Malcolm, Daniel J. Nasrallah, Timothy Gallagher^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

5 Citations (Scopus)

Abstract

Various alkoxy-substituted heterocyclic stannanes provide access to the corresponding substituted 'pyridone' moieties via Stille cross-coupling. Both pyridyl and a series of diazinyl stannanes are prepared, and options for unmasking (via demethylation or debenzylation) of the pyridone unit are evaluated.

Original language	English
Pages (from-to)	1904-1908
Number of pages	5
Journal	Synlett
Volume	25
Issue number	13
DOIs	https://doi.org/10.1055/s-0034-1378331
Publication status	Published - Aug 2014

Keywords

pyridine
heterocyclic stannane
Stille coupling
STANNYLATION REACTIONS
EXCHANGE-REACTIONS
(-)-CYTISINE
CYTISINE
ARYL

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@article{1284e62a9fe349ca9fe43e32206bd1b7,

title = "Synthesis of Mono- and Diaza-'Pyridones' via Stille Coupling of Alkoxystannanes",

abstract = "Various alkoxy-substituted heterocyclic stannanes provide access to the corresponding substituted 'pyridone' moieties via Stille cross-coupling. Both pyridyl and a series of diazinyl stannanes are prepared, and options for unmasking (via demethylation or debenzylation) of the pyridone unit are evaluated.",

keywords = "pyridine, heterocyclic stannane, Stille coupling, STANNYLATION REACTIONS, EXCHANGE-REACTIONS, (-)-CYTISINE, CYTISINE, ARYL",

author = "Smith, \{Charlotte L.\} and Christoph Hirschhaeuser and Malcolm, \{Georgia K.\} and Nasrallah, \{Daniel J.\} and Timothy Gallagher",

year = "2014",

month = aug,

doi = "10.1055/s-0034-1378331",

language = "English",

volume = "25",

pages = "1904--1908",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "13",

}

TY - JOUR

T1 - Synthesis of Mono- and Diaza-'Pyridones' via Stille Coupling of Alkoxystannanes

AU - Smith, Charlotte L.

AU - Hirschhaeuser, Christoph

AU - Malcolm, Georgia K.

AU - Nasrallah, Daniel J.

AU - Gallagher, Timothy

PY - 2014/8

Y1 - 2014/8

N2 - Various alkoxy-substituted heterocyclic stannanes provide access to the corresponding substituted 'pyridone' moieties via Stille cross-coupling. Both pyridyl and a series of diazinyl stannanes are prepared, and options for unmasking (via demethylation or debenzylation) of the pyridone unit are evaluated.

AB - Various alkoxy-substituted heterocyclic stannanes provide access to the corresponding substituted 'pyridone' moieties via Stille cross-coupling. Both pyridyl and a series of diazinyl stannanes are prepared, and options for unmasking (via demethylation or debenzylation) of the pyridone unit are evaluated.

KW - pyridine

KW - heterocyclic stannane

KW - Stille coupling

KW - STANNYLATION REACTIONS

KW - EXCHANGE-REACTIONS

KW - (-)-CYTISINE

KW - CYTISINE

KW - ARYL

U2 - 10.1055/s-0034-1378331

DO - 10.1055/s-0034-1378331

M3 - Article (Academic Journal)

SN - 0936-5214

VL - 25

SP - 1904

EP - 1908

JO - Synlett

JF - Synlett

IS - 13

ER -

Synthesis of Mono- and Diaza-'Pyridones' via Stille Coupling of Alkoxystannanes

Abstract

Keywords

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