Synthesis of nanobioglass and formation of apatite rods to occlude exposed dentine tubules and eliminate hypersensitivity

AR Curtis, NX West, B Su

Research output: Contribution to journalArticle (Academic Journal)peer-review

49 Citations (Scopus)

Abstract

The occlusion of patent dentine tubules may reduce or eliminate hypersensitivity by restricting dentinal fluid movement. The efficacy of a novel sol-gel nanobioglass and a melt-derived bioglass to occlude tubules and promote apatite formation was tested by mechanically brushing a slurry of bioglass powder and human saliva onto dentine possessing exposed tubules. Scanning electron microscopy, focused ion beam and energy-dispersive X-ray spectroscopy were used to characterize the powders and assess tubule occlusion. Melt-derived bioglass possessed an irregular particle morphology and had a mean size of 3.30 +/- 0.42 microm. The sol-gel bioglass particles were spherical, with a mean size of 0.65 +/- 0.19 microm. Dentine treated with melt-derived bioglass exhibited a tightly adherent continuous apatite layer. Treatment with nanobioglass resulted in particle deposition within tubules and formation of apatite rods which were tightly adherent to tubule walls and continuous to a measured depth of 270 microm.

Translated title of the contributionSynthesis of nanobioglass and formation of apatite rods to occlude exposed dentine tubules and eliminate hypersensitivity
Original languageEnglish
Pages (from-to)3740 - 3746
Number of pages7
JournalActa Biomaterialia
Volume6
Issue number9
DOIs
Publication statusPublished - Sep 2010

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