Target highlights in CASP13: experimental target structures through the eyes of their authors

Rosalba Lepore; Andriy Kryshtafovych; Markus Alahuhta; Harshul  Veraszto; Yannick  Bomble; Josh C Bufton; Alex N Bullock; Cody  Caba; Hongnan Coa; Owen Davies; Ambroise Desfosses; Matthew Dunne; Krzysztof  Fidelis; Celia Goulding; Manickam  Gurusanran; Irina  Gutsche; Christopher Harding; Marcus  Hartmann; Christopher S.  Hayes; Andrzej Joachimiak; Petr Leiman; Peter Loppnau; Andrew Lovering; Vladimir Y Lunin; Karolina Michalska; Ignacio Mir-Sanchis; Alok Mitra; John Moult; George Philips; Daniel M. Pinkas; Phoebe Rice; Yefeng Tong; Maya Topf; Jonathan Walton; Torsten Schwede

doi:10.1002/prot.25805

Target highlights in CASP13: experimental target structures through the eyes of their authors

Rosalba Lepore
, Andriy Kryshtafovych
, Markus Alahuhta
, Harshul Veraszto
, Yannick Bomble
, Josh C Bufton
, Alex N Bullock
, Cody Caba
, Hongnan Coa
, Owen Davies
, Ambroise Desfosses
, Matthew Dunne
, Krzysztof Fidelis
, Celia Goulding
, Manickam Gurusanran
, Irina Gutsche
, Christopher Harding
, Marcus Hartmann
, Christopher S. Hayes
, Andrzej Joachimiak

Petr Leiman, Peter Loppnau, Andrew Lovering, Vladimir Y Lunin, Karolina Michalska, Ignacio Mir-Sanchis, Alok Mitra, John Moult, George Philips, Daniel M. Pinkas, Phoebe Rice, Yefeng Tong, Maya Topf, Jonathan Walton, Torsten Schwede

Bristol Doctoral College

Research output: Contribution to journal › Article (Academic Journal) › peer-review

11 Citations (Scopus)

181 Downloads (Pure)

Abstract

The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

Original language	English
Number of pages	21
Journal	Proteins: Structure, Function, and Bioinformatics
Early online date	9 Sept 2019
DOIs	https://doi.org/10.1002/prot.25805
Publication status	E-pub ahead of print - 9 Sept 2019

Keywords

CASP
protein structure prediction
cryo‐EM
X‐ray crystallography

Access to Document

10.1002/prot.25805

Full-text PDF (accepted author manuscript)
This is the author accepted manuscript (AAM). The final published version (version of record) is available online via Wiley at https://onlinelibrary.wiley.com/doi/full/10.1002/prot.25805. Please refer to any applicable terms of use of the publisher.
Accepted author manuscript, 365 KB
Supplementary information PDF Accepted author manuscript, 1.86 MB

Handle.net

Persistent link

Cite this

Lepore, R., Kryshtafovych, A., Alahuhta, M., Veraszto, H., Bomble, Y., Bufton, J. C., Bullock, A. N., Caba, C., Coa, H., Davies, O., Desfosses, A., Dunne, M., Fidelis, K., Goulding, C., Gurusanran, M., Gutsche, I., Harding, C., Hartmann, M., Hayes, C. S., ... Schwede, T. (2019). Target highlights in CASP13: experimental target structures through the eyes of their authors. Proteins: Structure, Function, and Bioinformatics. Advance online publication. https://doi.org/10.1002/prot.25805

@article{c86acd978b34490fa111f0003eccf70a,

title = "Target highlights in CASP13: experimental target structures through the eyes of their authors",

abstract = "The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.",

keywords = "CASP, protein structure prediction, cryo‐EM, X‐ray crystallography",

author = "Rosalba Lepore and Andriy Kryshtafovych and Markus Alahuhta and Harshul Veraszto and Yannick Bomble and Bufton, \{Josh C\} and Bullock, \{Alex N\} and Cody Caba and Hongnan Coa and Owen Davies and Ambroise Desfosses and Matthew Dunne and Krzysztof Fidelis and Celia Goulding and Manickam Gurusanran and Irina Gutsche and Christopher Harding and Marcus Hartmann and Hayes, \{Christopher S.\} and Andrzej Joachimiak and Petr Leiman and Peter Loppnau and Andrew Lovering and Lunin, \{Vladimir Y\} and Karolina Michalska and Ignacio Mir-Sanchis and Alok Mitra and John Moult and George Philips and Pinkas, \{Daniel M.\} and Phoebe Rice and Yefeng Tong and Maya Topf and Jonathan Walton and Torsten Schwede",

year = "2019",

month = sep,

day = "9",

doi = "10.1002/prot.25805",

language = "English",

journal = "Proteins: Structure, Function, and Bioinformatics",

issn = "0887-3585",

publisher = "Wiley-Liss Inc.",

}

Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, H, Bomble, Y, Bufton, JC, Bullock, AN, Caba, C, Coa, H, Davies, O, Desfosses, A, Dunne, M, Fidelis, K, Goulding, C, Gurusanran, M, Gutsche, I, Harding, C, Hartmann, M, Hayes, CS, Joachimiak, A, Leiman, P, Loppnau, P, Lovering, A, Lunin, VY, Michalska, K, Mir-Sanchis, I, Mitra, A, Moult, J, Philips, G, Pinkas, DM, Rice, P, Tong, Y, Topf, M, Walton, J & Schwede, T 2019, 'Target highlights in CASP13: experimental target structures through the eyes of their authors', Proteins: Structure, Function, and Bioinformatics. https://doi.org/10.1002/prot.25805

TY - JOUR

T1 - Target highlights in CASP13

T2 - experimental target structures through the eyes of their authors

AU - Lepore, Rosalba

AU - Kryshtafovych, Andriy

AU - Alahuhta, Markus

AU - Veraszto, Harshul

AU - Bomble, Yannick

AU - Bufton, Josh C

AU - Bullock, Alex N

AU - Caba, Cody

AU - Coa, Hongnan

AU - Davies, Owen

AU - Desfosses, Ambroise

AU - Dunne, Matthew

AU - Fidelis, Krzysztof

AU - Goulding, Celia

AU - Gurusanran, Manickam

AU - Gutsche, Irina

AU - Harding, Christopher

AU - Hartmann, Marcus

AU - Hayes, Christopher S.

AU - Joachimiak, Andrzej

AU - Leiman, Petr

AU - Loppnau, Peter

AU - Lovering, Andrew

AU - Lunin, Vladimir Y

AU - Michalska, Karolina

AU - Mir-Sanchis, Ignacio

AU - Mitra, Alok

AU - Moult, John

AU - Philips, George

AU - Pinkas, Daniel M.

AU - Rice, Phoebe

AU - Tong, Yefeng

AU - Topf, Maya

AU - Walton, Jonathan

AU - Schwede, Torsten

PY - 2019/9/9

Y1 - 2019/9/9

N2 - The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

AB - The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

KW - CASP

KW - protein structure prediction

KW - cryo‐EM

KW - X‐ray crystallography

U2 - 10.1002/prot.25805

DO - 10.1002/prot.25805

M3 - Article (Academic Journal)

C2 - 31442339

SN - 0887-3585

JO - Proteins: Structure, Function, and Bioinformatics

JF - Proteins: Structure, Function, and Bioinformatics

ER -

Target highlights in CASP13: experimental target structures through the eyes of their authors

Abstract

Keywords

Access to Document

Handle.net

Fingerprint

Cite this