The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood

Scott Chiesa*, Alicja Rapala, Marietta Charakida, Kaitlin H Wade, Nicholas John Timpson, John E Deanfield

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

Abstract

Rising rates of adiposity in the young pose one of the greatest threats to future population burden of cardiovascular disease. Understanding the contribution of genetic and early-life influences to adiposity profiles in young adulthood – when the first signs of subclinical cardiovascular disease commonly appear – are vital if effective lifetime prevention strategies are to be developed. This data note documents the extensive range of genotypic and phenotypic data available from a London-based sub-study of the long-running Avon Longitudinal Study of Parents and Children (ALSPAC)—the ‘ALSPAC in London’ Study—in which extensive adipose and cardiovascular phenotyping was carried out in participants recruited based on a genetic predisposition to obesity.
Original languageEnglish
JournalWellcome Open Research
Volume3
Issue number162
Publication statusPublished - 23 Dec 2018

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