The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood

Scott Chiesa*, Alicja Rapala, Marietta Charakida, Kaitlin H Wade, Nicholas John Timpson, John E Deanfield

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

Rising rates of adiposity in the young pose one of the greatest threats to future population burden of cardiovascular disease. Understanding the contribution of genetic and early-life influences to adiposity profiles in young adulthood – when the first signs of subclinical cardiovascular disease commonly appear – are vital if effective lifetime prevention strategies are to be developed. This data note documents the extensive range of genotypic and phenotypic data available from a London-based sub-study of the long-running Avon Longitudinal Study of Parents and Children (ALSPAC)—the ‘ALSPAC in London’ Study—in which extensive adipose and cardiovascular phenotyping was carried out in participants recruited based on a genetic predisposition to obesity.
Original languageEnglish
JournalWellcome Open Research
Volume3
Issue number162
Publication statusPublished - 23 Dec 2018

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