The association between autistic spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) Birth Cohort

Sarah A Sullivan; Dheeraj Rai; Jean Golding (nee Fedrick); Stanley Zammit; Colin D Steer

The association between autistic spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) Birth Cohort

Sarah A Sullivan, Dheeraj Rai, Jean Golding (nee Fedrick), Stanley Zammit, Colin D Steer

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Abstract

Objective: Studies report overlap between autism spectrum disorders and psychosis. This may indicate a relationship between the two disorders or an artificial overlap due to similarity of symptoms. The aim of this study was to investigate whether autism spectrum disorder and autistic traits predict psychotic experiences in early adolescence.
Method: This study analyses prospective data from a cohort. A dataset of 5359 cohort members was analysed who had provided data on autistic traits and/or a diagnosis of an autism spectrum disorder and psychotic experiences at age 12.
Results: A diagnosis of an autism spectrum disorder (OR 2.81 95% CI 1.07, 7.34 p=0.035) and childhood autistic traits (OR 1.15 95% CI 1.05, 1.26 p=0.0018) were associated with psychotic experiences after adjustment for confounders.
Conclusions: These findings suggest a shared neuro-developmental origin for autism and psychosis.

Original language	English
Pages (from-to)	806 - 814
Journal	Journal of the American Academy of Child and Adolescent
Volume	52
Issue number	8
Publication status	Published - 2013

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1 Article (Academic Journal)

The longitudinal associations between social functioning and theory of mind in first episode psychosis
Sullivan, S. A., Lewis, G. H., Mohr, C., Herzig, D., Corcoran, R., Drake, R. & Evans, J., 2013, In: Cognitive Neuropsychiatry. 23 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review
6 Citations (Scopus)

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title = "The association between autistic spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) Birth Cohort",

abstract = "Objective: Studies report overlap between autism spectrum disorders and psychosis. This may indicate a relationship between the two disorders or an artificial overlap due to similarity of symptoms. The aim of this study was to investigate whether autism spectrum disorder and autistic traits predict psychotic experiences in early adolescence.Method: This study analyses prospective data from a cohort. A dataset of 5359 cohort members was analysed who had provided data on autistic traits and/or a diagnosis of an autism spectrum disorder and psychotic experiences at age 12.Results: A diagnosis of an autism spectrum disorder (OR 2.81 95% CI 1.07, 7.34 p=0.035) and childhood autistic traits (OR 1.15 95% CI 1.05, 1.26 p=0.0018) were associated with psychotic experiences after adjustment for confounders. Conclusions: These findings suggest a shared neuro-developmental origin for autism and psychosis.",

author = "Sullivan, {Sarah A} and Dheeraj Rai and {Golding (nee Fedrick)}, Jean and Stanley Zammit and Steer, {Colin D}",

year = "2013",

language = "English",

volume = "52",

pages = "806 -- 814",

journal = "Journal of the American Academy of Child and Adolescent",

number = "8",

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The association between autistic spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) Birth Cohort. / Sullivan, Sarah A ; Rai, Dheeraj ; Golding (nee Fedrick), Jean et al.
In: Journal of the American Academy of Child and Adolescent, Vol. 52, No. 8, 2013, p. 806 - 814.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - The association between autistic spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) Birth Cohort

AU - Sullivan, Sarah A

AU - Rai, Dheeraj

AU - Golding (nee Fedrick), Jean

AU - Zammit, Stanley

AU - Steer, Colin D

PY - 2013

Y1 - 2013

N2 - Objective: Studies report overlap between autism spectrum disorders and psychosis. This may indicate a relationship between the two disorders or an artificial overlap due to similarity of symptoms. The aim of this study was to investigate whether autism spectrum disorder and autistic traits predict psychotic experiences in early adolescence.Method: This study analyses prospective data from a cohort. A dataset of 5359 cohort members was analysed who had provided data on autistic traits and/or a diagnosis of an autism spectrum disorder and psychotic experiences at age 12.Results: A diagnosis of an autism spectrum disorder (OR 2.81 95% CI 1.07, 7.34 p=0.035) and childhood autistic traits (OR 1.15 95% CI 1.05, 1.26 p=0.0018) were associated with psychotic experiences after adjustment for confounders. Conclusions: These findings suggest a shared neuro-developmental origin for autism and psychosis.

AB - Objective: Studies report overlap between autism spectrum disorders and psychosis. This may indicate a relationship between the two disorders or an artificial overlap due to similarity of symptoms. The aim of this study was to investigate whether autism spectrum disorder and autistic traits predict psychotic experiences in early adolescence.Method: This study analyses prospective data from a cohort. A dataset of 5359 cohort members was analysed who had provided data on autistic traits and/or a diagnosis of an autism spectrum disorder and psychotic experiences at age 12.Results: A diagnosis of an autism spectrum disorder (OR 2.81 95% CI 1.07, 7.34 p=0.035) and childhood autistic traits (OR 1.15 95% CI 1.05, 1.26 p=0.0018) were associated with psychotic experiences after adjustment for confounders. Conclusions: These findings suggest a shared neuro-developmental origin for autism and psychosis.

M3 - Article (Academic Journal)

VL - 52

SP - 806

EP - 814

JO - Journal of the American Academy of Child and Adolescent

JF - Journal of the American Academy of Child and Adolescent

IS - 8

ER -

The association between autistic spectrum disorder and psychotic experiences in the Avon Longitudinal Study of Parents and Children (ALSPAC) Birth Cohort

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Research output

The longitudinal associations between social functioning and theory of mind in first episode psychosis

Cite this