TY - JOUR
T1 - The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019
T2 - Findings from the Global Burden of Disease Study 2019
AU - Castelpietra, Giulio
AU - Knudsen, Ann Kristin Skrindo
AU - Agardh, Emilie E.
AU - Armocida, Benedetta
AU - Beghi, Massimiliano
AU - Iburg, Kim Moesgaard
AU - Logroscino, Giancarlo
AU - Ma, Rui
AU - Starace, Fabrizio
AU - Steel, Nicholas
AU - Addolorato, Giovanni
AU - Andrei, Catalina Liliana
AU - Andrei, Tudorel
AU - Ayuso-Mateos, Jose L.
AU - Banach, Maciej
AU - Bärnighausen, Till Winfried
AU - Barone-Adesi, Francesco
AU - Bhagavathula, Akshaya Srikanth
AU - Carvalho, Felix
AU - Madureira-Carvalho, Áurea M.
AU - Chandan, Joht Singh
AU - Chattu, Vijay Kumar
AU - Couto, Rosa A.S.
AU - Cruz-Martins, Natália
AU - Dargan, Paul I.
AU - Deuba, Keshab
AU - Silva, Diana Dias da
AU - Fagbamigbe, Adeniyi Francis
AU - Fernandes, Eduarda
AU - Ferrara, Pietro
AU - Fischer, Florian
AU - Gaal, Peter Andras
AU - Gialluisi, Alessandro
AU - Haagsma, Juanita A.
AU - Haro, Josep Maria
AU - Hasan, M. Tasdik
AU - Hasan, Syed Shahzad
AU - Hostiuc, Sorin
AU - Iacoviello, Licia
AU - Iavicoli, Ivo
AU - Jamshidi, Elham
AU - Jonas, Jost B.
AU - Joo, Tamas
AU - Jozwiak, Jacek Jerzy
AU - Katikireddi, Srinivasa Vittal
AU - Kauppila, Joonas H.
AU - Khan, Moien A.B.
AU - Kisa, Adnan
AU - Kisa, Sezer
AU - Kivimäki, Mika
AU - Koly, Kamrun Nahar
AU - Koyanagi, Ai
AU - Kumar, Manasi
AU - Lallukka, Tea
AU - Langguth, Berthold
AU - Ledda, Caterina
AU - Lee, Paul H.
AU - Lega, Ilaria
AU - Linehan, Christine
AU - Loureiro, Joana A.
AU - Madureira-Carvalho, Áurea M.
AU - Martinez-Raga, Jose
AU - Mathur, Manu Raj
AU - McGrath, John J.
AU - Mechili, Enkeleint A.
AU - Mentis, Alexios Fotios A.
AU - Mestrovic, Tomislav
AU - Miazgowski, Bartosz
AU - Mirica, Andreea
AU - Mirijello, Antonio
AU - Moazen, Babak
AU - Mohammed, Shafiu
AU - Mulita, Francesk
AU - Nagel, Gabriele
AU - Negoi, Ruxandra Irina
AU - Negoi, Ruxandra Irina
AU - Nwatah, Vincent Ebuka
AU - Padron-Monedero, Alicia
AU - Panda-Jonas, Songhomitra
AU - Pardhan, Shahina
AU - Pasovic, Maja
AU - Patel, Jay
AU - Petcu, Ionela Roxana
AU - Pinheiro, Marina
AU - Pollok, Richard Charles G.
AU - Postma, Maarten J.
AU - Rawaf, David Laith
AU - Rawaf, Salman
AU - Romero-Rodríguez, Esperanza
AU - Ronfani, Luca
AU - Sagoe, Dominic
AU - Sanmarchi, Francesco
AU - Schaub, Michael P.
AU - Sharew, Nigussie Tadesse
AU - Shiri, Rahman
AU - Shokraneh, Farhad
AU - Sigfusdottir, Inga Dora
AU - Silva, João Pedro
AU - Silva, Renata
AU - Socea, Bogdan
AU - Szócska, Miklós
AU - Tabarés-Seisdedos, Rafael
AU - Torrado, Marco
AU - Tovani-Palone, Marcos Roberto
AU - Vasankari, Tommi Juhani
AU - Veroux, Massimiliano
AU - Viner, Russell M.
AU - Werdecker, Andrea
AU - Winkler, Andrea Sylvia
AU - Hay, Simon I.
AU - Ferrari, Alize J.
AU - Naghavi, Mohsen
AU - Allebeck, Peter
AU - Monasta, Lorenzo
N1 - Publisher Copyright:
© 2022 The Author(s).
PY - 2022/5/1
Y1 - 2022/5/1
N2 - Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time. Methods: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated. Findings: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 – 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432–912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9–412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (–29·1%;23·8-38·5). YLLs decreased in self-harm (–27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs. Interpretation: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. Funding: The Bill and Melinda Gates Foundation
AB - Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time. Methods: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated. Findings: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 – 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432–912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9–412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (–29·1%;23·8-38·5). YLLs decreased in self-harm (–27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs. Interpretation: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. Funding: The Bill and Melinda Gates Foundation
UR - https://kclpure.kcl.ac.uk/portal/en/publications/0afee1b7-5bd3-489d-bf3c-67b48843f5db
U2 - 10.1016/j.lanepe.2022.100341
DO - 10.1016/j.lanepe.2022.100341
M3 - Article (Academic Journal)
C2 - 35392452
SN - 2666-7762
VL - 16
JO - The Lancet Regional Health - Europe
JF - The Lancet Regional Health - Europe
M1 - 100341
ER -