The CUIDEME Study: determinants of burden in chilean primary caregivers of patients with dementia

Andrea Slachevsky, Marilu Budinich, Claudia Miranda-Castillo, Javier Núñez-Huasaf, Jaime R Silva, Carlos Muñoz-Neira, Sergio Gloger, Oscar Jimenez, Bernardo Martorell, Carolina Delgado

Research output: Contribution to journalArticle (Academic Journal)peer-review

31 Citations (Scopus)


BACKGROUND: Caring for a person with dementia is associated with well-documented increases in burden and distress and decreases in mental health and wellbeing. Studies assessing burden in caregivers of patients with dementia and its determinants are scarce in Latin America.

OBJECTIVE: The main objective of this study was to assess the extent and the determinants of burden in informal primary caregivers of patients with dementia in Chile.

METHODS: A descriptive study was conducted using clinically validated scales to assess dementia characteristics and to measure caregiver variables. Family socio-demographic characteristics and functional status, patient functional dependency and behavioral disturbances, and caregiver psychiatric morbidity were analyzed as independent variables to determine caregiver burden.

RESULTS: Two hundred and ninety-two informal caregivers were included. There were more female (80%) than male caregivers, consisting mainly of daughters and spouses of the patients. Severe burden was reported in 63% of the caregivers, and 47% exhibited psychiatric morbidity. Burden was associated with caregiver psychiatric distress, family dysfunction, severity of neuropsychiatric symptoms and functional disability, but neither patient age, gender, nor socioeconomic status impacted burden.

CONCLUSION: Our results underscore the importance of assessing the consequences of dementia in both caregivers and patients in order to evaluate the real biopsychosocial impact of dementia, as well as the importance of planning appropriate and effective public health interventions in Latin American countries. In addition, interventions targeting caregiver psychological distress, caregiver familial dysfunction, patient neuropsychiatric disorders, and patient functional disability could potentially diminish caregiver burden.

Original languageEnglish
Pages (from-to)297-306
Number of pages10
JournalJournal of Alzheimer's Disease
Issue number2
Publication statusPublished - 2013


  • Adult
  • Aged
  • Aged, 80 and over
  • Caregivers
  • Chile
  • Cost of Illness
  • Data Interpretation, Statistical
  • Dementia
  • Educational Status
  • Family
  • Female
  • Humans
  • Income
  • Insurance, Health
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales
  • Sex Factors
  • Socioeconomic Factors
  • Surveys and Questionnaires
  • Urban Population
  • Alzheimer's disease
  • caregiver
  • dependency
  • dependency burden
  • general health questionnaire
  • mental health
  • neuropsychiatric inventory
  • psychological distress
  • Zarit burden interview

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