The early development phases of a European Organisation for Research and Treatment of Cancer (EORTC) module to assess patient reported outcomes (PROs) in women undergoing breast reconstruction

Zoe E Winters

Research output: Contribution to journalArticle (Academic Journal)peer-review

11 Citations (Scopus)

Abstract

Abstract Introduction: A comprehensive evaluation of breast reconstruction (BRR) surgery includes measurement of patient reported outcomes (PROs). There is, however, a lack of val- idated BRR-specific PRO measures (PROMs) that adequately assess relevant issues. This study is developing a European Organisation for Research and Treatment of Cancer (EORTC) questionnaire/module specific for PROs in BRR to supplement the cancer-core and breast cancer EORTC questionnaires, respectively: the QLQ-C30 and QLQ-BR23. Methods: Phases I and II of questionnaire development followed EORTC guidelines including a systematic literature review to identify all potential ‘issues’ (concepts relevant to PROs) and semi-structured interviews with 89 patients and 9 European multi-disciplinary health care pro- fessionals (HCPs) (Sweden, Italy and the United Kingdom [UK]). Interviewers asked partic- ipants the ‘relevance’ of outcomes identified in the literature and captured additional ‘issues’ of importance.
Results: The literature search and interviews of patients and HCPs yielded 69 issues relating to BRR operationalised into 31 provisional items (single questions) for the module, which was conceptualised to contain five scales: treatment/surgery related symptoms (affecting the shoul- der, arm and reconstructed breast), body image, sexuality, cosmetic outcomes (pertaining to three areas: breast, donor site and nipple) and overall satisfaction.
Discussion: The provisional development of the EORTC BRR module has 31 items address- ing issues of importance to patients as well as HCPs. Further international testing is underway as a UK National Cancer Research Network trial to ensure that this PROM will be psycho- metrically and clinically robust and applicable for use in clinical trials, cohort studies, national audit and clinical practice.
2012 Published by Elsevier Ltd.
Original languageEnglish
Number of pages10
JournalEuropean Journal of Cancer
DOIs
Publication statusPublished - 12 Oct 2012

Bibliographical note

Copyright © 2012. Published by Elsevier Ltd.

Keywords

  • EORTC, developmental questionnaire, PROMs, breast reconstruction

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