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OBJECTIVE: Investigate the effects of administration of meloxicam and carprofen on the mobility of hens with and without keel fractures.
STUDY DESIGN: Within each of two experiments a 'blinded' randomised cross over design whereby birds received either the test drug (carprofen or meloxicam) or saline.
ANIMALS: Two groups of Lohman Brown hens with and without keel bone fractures.
METHODS: The first group (n = 63) was treated with carprofen 25 mg kg(-1) and saline subcutaneously, twice. The second group (n = 40) was treated with meloxicam (5 mg kg(-1) ) and saline subcutaneously. The latency of birds to fly down from perches 50, 100 and 150 cm above the ground was measured after each treatment. Data from experiment 1 and 2 were analysed separately; the effects of drug treatment compared with saline on landing time for birds with and without keel bone fractures were evaluated using MLwiN.
RESULTS: In both experiments latency to fly down from perches was longer in hens with keel fractures and there was a significant interaction between perch height and fracture status. For carprofen, at the 50 cm, 100 cm and 150 cm perch heights, birds with fractures took (mean ± SD) 2.5 ± 2.9, 6.8 ± 9.7 and 11.5 ± 13.2 seconds respectively to fly down compared with 1.3 ± 0.5, 2.3 ± 1.2 and 4.2 ± 3.1 seconds for birds without fractures. For meloxicam, at the 50 cm, 100 cm and 150 cm perch heights, birds with fractures took 2.9 ± 2.5, 49.8 ± 85.4 and 100.3 ± 123.6 seconds respectively compared with 0.7 ± 0.5, 2.5 ± 7.1 and 3.0 ± 4.6 seconds to fly down for birds without fractures. There was no significant effect of carprofen or meloxicam treatment.
CONCLUSION AND CLINICAL RELEVANCE: These data provide further confirmation that keel fractures reduce the willingness of birds to move from perches.
Bibliographical note© 2014 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesia and Analgesia.
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EVALUATION OF PAIN EXPERIENCE IN DOMESTIC FOWL: ASSOCIATIONS BETWEEN CLINICAL SYMPTOMS, BIOCHEMICAL MARKERS AND BIRD SELF-SELECTION OF ANALGESICS
Waterman-Pearson, A. E.
1/06/09 → 1/12/12