The emerging importance of ultradian glucocorticoid rhythms within metabolic pathology

Research output: Contribution to journalArticle (Academic Journal)

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Abstract

Glucocorticoid (GC) hormones play significant roles within homeostasis and the chrono-dynamics of their regulatory role has become increasingly recognised within dysregulated GC pathology, particularly with metabolic phenotypes. Within this article, we will discuss the relevance of the ultradian homeostatic rhythm, how its dysregulation effects glucocorticoid receptor and RNA polymeraseII recruitment and may play a significant role within aberrant metabolic action.

Original languageEnglish
Pages (from-to)112-114
Number of pages3
JournalAnnales d'Endocrinologie
Volume79
Issue number3
Early online date5 Apr 2018
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • Glucocorticoid receptor
  • Glucocorticoids
  • Metabolism
  • RNA polymeraseII
  • Synthetic steroids
  • Ultradian

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