The Functional Effects of Cigarette Smoking in Women on the Lower Urinary Tract

Chendrimada Madhu, Doyo Enki, Musaab Yassin, Marcus Drake, Hashim Hashim

Research output: Contribution to journalArticle (Academic Journal)peer-review

28 Citations (Scopus)
401 Downloads (Pure)


Methods: Methods: Methods: AAim: The aim of the study was to evaluate the urodynamic findings in women who smoke cigarettes, with bothersome lower urinary tract symptoms, to help develop an understanding of potential impact of smoking on the lower urinary tract function.

A database of 11,678 women who underwent urodynamic testing in a tertiary referral centre in the United Kingdom, from January 1991 to December 2009 was retrospectively analysed. All women reporting cigarette smoking were included in the study group. Urodynamic testing and interpretation of results were done in accordance with the recommendations of the International Continence Society.

Results: Overall, 2,476 (21.2%) women reported smoking cigarettes. Overactive bladder symptoms (OAB) were more common in smokers (OR 1.14, p = 0.006). Female smokers significantly complained of secondary nocturnal enuresis (OR 2.26, p < 0.001) and coital incontinence (CI; OR 1.14, p < 0.001). Detrusor overactivity (DO; OR 1.42, p < 0.001) and detrusor overactivity incontinence (DOI; OR 1.42, p < 0.001) were the most significant urodynamic findings. Smoking was not shown to be significantly associated with SUI (OR 1.08, p = 0.213) or urodynamic stress incontinence (OR 0.86, p = 0.001).

Cigarette smoking is associated with OAB, secondary nocturnal enuresis and CI. DO and DOI are the most significant urodynamic findings.
Original languageEnglish
Pages (from-to)478-482
Number of pages5
JournalUrologia Internationalis
Issue number4
Early online date10 Oct 2015
Publication statusPublished - Dec 2015

Structured keywords

  • Centre for Surgical Research


  • Adult onset nocturnal enuresis
  • Cigarette smoking
  • Detrusor overactivity
  • Detrusor overactivity incontinence
  • Stress urinary incontinence
  • Urodynamics


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