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The genetic lottery goes to school: better schools compensate for the effects of student's genetic differences

  • Rosa Cheesman*
  • , Nicolai Borgen
  • , Astrid Sandsor
  • , Paul Hufe
  • *Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

n this paper, we investigate whether better schools can compensate for the effects of children’s genetic differences. To this end, we combine data from the Norwegian Mother, Father, and Child Cohort Study (MoBa) with Norwegian register data to estimate the interaction between measures of children’s predisposition to education and school quality. We use MoBa’s genetic data to compute polygenic indices for educational attainment (PGIEA). Importantly, MoBa includes genetic data on mother-father-child trios, allowing us to identify causal genetic effects using within-family variation. We calculate school value-added measures from Norwegian register data, allowing us to causally estimate school quality effects. Leveraging the advantages of both data sources, we provide a causally identified study of gene–environment interactions in the school context. We find evidence for substitutability of PGIEA and school quality in reading but not numeracy: A 1 SD increase of school quality decreases the impact of a 1 SD increase of PGIEA on reading test scores by 6%. The substitutability arises through gains of students at the lower end of the PGIEA distribution. This suggests that investments in school quality may help reduce educational inequalities arising from genetic differences between students.
Original languageEnglish
Article numbere2511715122
Number of pages10
JournalProceedings of the National Academy of Sciences
Volume122
Issue number43
Early online date24 Oct 2025
DOIs
Publication statusPublished - 28 Oct 2025

Bibliographical note

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Copyright © 2025 the Author(s).

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