The HPA axis in major depression: classical theories and new developments

Carmine M Pariante, Stafford L Lightman

Research output: Contribution to journalArticle (Academic Journal)peer-review

1069 Citations (Scopus)

Abstract

Studies over the last 40 years have demonstrated that hyperactivity of the hypothalamic-pituitary-adrenal axis is one of the most consistent biological findings in major depression psychiatry, but the mechanisms underlying this abnormality are still unclear.
Original languageEnglish
Pages (from-to)464-8
Number of pages5
JournalTrends in Neurosciences
Volume31
Issue number9
DOIs
Publication statusPublished - 2008

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