Abstract
All organisms are connected in a complex web of relationships. Although many of these are benign, not all are, and everything alive devotes significant resources to identifying and neutralizing threats from other species. From bacteria through to primates, the presence of some kind of effective immune system has gone hand in hand with evolutionary success. This article focuses on mammalian immunity, the challenges that it faces, the mechanisms by which these are addressed, and the consequences that arise when it malfunctions.
“Great fleas have little fleas upon their backs to bite 'em, And little fleas have lesser fleas, and so ad infinitum.” Augustus De Morgan (1872)
“Great fleas have little fleas upon their backs to bite 'em, And little fleas have lesser fleas, and so ad infinitum.” Augustus De Morgan (1872)
| Original language | English |
|---|---|
| Pages (from-to) | 275-301 |
| Number of pages | 27 |
| Journal | Essays in Biochemistry |
| Volume | 60 |
| Issue number | 3 |
| Early online date | 26 Oct 2016 |
| DOIs | |
| Publication status | Published - 26 Oct 2016 |
Keywords
- basic
- immunology
- review
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