The impact of study size on meta-analyses: examination of underpowered studies in Cochrane reviews

Rebecca M Turner, Sheila M Bird, Julian P T Higgins

Research output: Contribution to journalArticle (Academic Journal)peer-review

294 Citations (Scopus)

Abstract

Most meta-analyses include data from one or more small studies that, individually, do not have power to detect an intervention effect. The relative influence of adequately powered and underpowered studies in published meta-analyses has not previously been explored. We examine the distribution of power available in studies within meta-analyses published in Cochrane reviews, and investigate the impact of underpowered studies on meta-analysis results.
Original languageEnglish
Pages (from-to)e59202
JournalPLoS ONE
Volume8
Issue number3
DOIs
Publication statusPublished - 2013

Fingerprint Dive into the research topics of 'The impact of study size on meta-analyses: examination of underpowered studies in Cochrane reviews'. Together they form a unique fingerprint.

Cite this