The Language of Calcium Signaling

Antony N. Dodd, Joerg Kudla, Dale Sanders

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

711 Citations (Scopus)

Abstract

Ca2+ signals are a core regulator of plant cell physiology and cellular responses to the environment. The channels, pumps, and carriers that underlie Ca2+ homeostasis provide the mechanistic basis for generation of Ca2+ signals by regulating movement of Ca2+ ions between subcellular compartments and between the cell and its extracellular environment. The information encoded within the Ca2+ transients is decoded and transmitted by a toolkit of Ca2+-binding proteins that regulate transcription via Ca2+-responsive promoter elements and that regulate protein phosphorylation. Ca2+-signaling networks have architectural structures comparable to scale-free networks and bow tie networks in computing, and these similarities help explain such properties of Ca2+-signaling networks as robustness, evolvability, and the ability to process multiple signals simultaneously.

Original languageEnglish
Title of host publicationAnnual Review of Plant Biology
Place of PublicationPALO ALTO
PublisherAnnual Reviews
Pages593-620
Number of pages28
DOIs
Publication statusPublished - 2010

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