Introduction. There is some cross-sectional evidence that theory of mind ability is
15 associated with social functioning in those with psychosis but the direction of this
relationship is unknown. This study investigates the longitudinal association
between both theory of mind and psychotic symptoms and social functioning
outcome in first-episode psychosis.
Methods. Fifty-four people with first-episode psychosis were followed up at 6 and
20 12 months. Random effects regression models were used to estimate the stability
of theory of mind over time and the association between baseline theory of mind
and psychotic symptoms and social functioning outcome.
Results. Neither baseline theory of mind ability (regression coefficients: Hinting
test 1.07 95% CI 0.74, 2.88; Visual Cartoon test 2.91 95% CI 7.32, 1.51)
25 nor baseline symptoms (regression coefficients: positive symptoms 0.04 95%
CI 1.24, 1.16; selected negative symptoms 0.15 95% CI 2.63, 2.32) were
associated with social functioning outcome. There was evidence that theory of
mind ability was stable over time, (regression coefficients: Hinting test 5.92 95%
CI 6.66, 8.92; Visual Cartoon test score 0.13 95% CI 0.17, 0.44).
30 Conclusions. Neither baseline theory of mind ability nor psychotic symptoms are
associated with social functioning outcome. Further longitudinal work is needed
to understand the origin of social functioning deficits in psychosis.