The MONitoring Dialysis Outcomes (MONDO) initiative

Len A Usvyat, Yosef S Haviv, Michael Etter, Jeroen Kooman, Daniele Marcelli, Cristina Marelli, Albert Power, Ted Toffelmire, Yuedong Wang, Peter Kotanko

Research output: Contribution to journalArticle (Academic Journal)peer-review

28 Citations (Scopus)

Abstract

BACKGROUND: Systematic collection and analysis of global hemodialysis patient data may help to improve patient outcomes.

METHODS: The MONitoring Dialysis Outcomes (MONDO) initiative comprises data from eight dialysis providers worldwide. Data are combined into one repository. Extensive procedures are employed to merge data across countries and providers.

RESULTS: The MONDO database comprises longitudinal data of currently 128,000 hemodialysis patients from 26 countries on five continents. Here we report data from 62,345 incident hemodialysis patients. We found lower catheter rates in South-East Asia and Australia, lower hemoglobin levels in South-East Asia, and a higher prevalence of diabetes in North America. Longitudinal analyses suggest that there is a decline in interdialytic weight gain and serum phosphorus and an increasing neutrophil-to-lymphocyte ratio before death in all regions studied.

CONCLUSIONS: While organizationally lean and low-cost, MONDO is the largest global dialysis database initiative to date, with a particular focus on high longitudinal data density and geographical diversity.

Original languageEnglish
Pages (from-to)37-48
Number of pages12
JournalBlood Purification
Volume35
Issue number1-3
DOIs
Publication statusPublished - 2013

Bibliographical note

Copyright © 2013 S. Karger AG, Basel.

Keywords

  • Aged
  • Body Weight
  • Databases, Factual
  • Electronic Health Records
  • Female
  • Hemoglobins
  • Humans
  • International Cooperation
  • Kidney Failure, Chronic
  • Leukocyte Count
  • Lymphocytes
  • Male
  • Middle Aged
  • Monitoring, Physiologic
  • Neutrophils
  • Phosphorus
  • Renal Dialysis
  • Survival Analysis
  • Treatment Outcome

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