The NuA4 histone acetyltransferase: variations on a theme of SAGA

Alan C M Cheung

doi:10.1038/s41594-023-01057-w

The NuA4 histone acetyltransferase: variations on a theme of SAGA

Alan C M Cheung

School of Biochemistry

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Abstract

NuA4 is a highly conserved histone acetyltransferase complex that functions in transcription and DNA repair. Four groups have recently determined the structure of NuA4 from two different yeasts using cryo-EM, revealing important mechanistic details of its function and allowing a detailed comparison to the related SAGA complex.

Original language	English
Pages (from-to)	1240-1241
Number of pages	2
Journal	Nature Structural and Molecular Biology
Volume	30
Early online date	7 Aug 2023
DOIs	https://doi.org/10.1038/s41594-023-01057-w
Publication status	Published - 1 Sept 2023

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This is the accepted author manuscript (AAM) of the article which has been made Open Access under the University of Bristol's Scholarly Works Policy. The final published version (Version of Record) can be found on the publisher's website. The copyright of any third-party content, such as images, remains with the copyright holder.
Accepted author manuscript, 520 KBLicence: CC BY

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abstract = "NuA4 is a highly conserved histone acetyltransferase complex that functions in transcription and DNA repair. Four groups have recently determined the structure of NuA4 from two different yeasts using cryo-EM, revealing important mechanistic details of its function and allowing a detailed comparison to the related SAGA complex.",

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The NuA4 histone acetyltransferase: variations on a theme of SAGA

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