The role of adrenaline in cardiopulmonary resuscitation

Christopher J.R. Gough, Jerry P. Nolan*

*Corresponding author for this work

Research output: Contribution to journalReview article (Academic Journal)peer-review

17 Citations (Scopus)
299 Downloads (Pure)


Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microcirculatory flow. It is possible that better short-term survival comes at the cost of worse long-term outcomes. This narrative review summarises the rationale for using adrenaline, significant studies to date, and ongoing research.
Original languageEnglish
Article number139
Number of pages8
JournalCritical Care
Issue number1
Publication statusPublished - 29 May 2018


  • Adrenaline
  • Cardiac arrest
  • Cardiopulmonary resuscitation
  • Epinephrine
  • Outcome

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