TY - JOUR
T1 - The role of socioeconomic status in the association of lung function and air pollution
T2 - a pooled analysis of three adult escape cohorts
AU - Keidel, Dirk
AU - Anto, Josep Maria
AU - Basagaña, Xavier
AU - Bono, Roberto
AU - Burte, Emilie
AU - Carsin, Anne Elie
AU - Forsberg, Bertil
AU - Fuertes, Elaine
AU - Galobardes, Bruna
AU - Heinrich, Joachim
AU - De Hoogh, Kees
AU - Jarvis, Debbie
AU - Künzli, Nino
AU - Leynaert, Bénédicte
AU - Marcon, Alessandro
AU - Le Moual, Nicole
AU - De Nazelle, Audrey
AU - Schindler, Christian
AU - Siroux, Valérie
AU - Stempfelet, Morgane
AU - Sunyer, Jordi
AU - Temam, Sofia
AU - Tsai, Ming Yi
AU - Varraso, Raphaëlle
AU - Jacquemin, Bénédicte
AU - Probst-Hensch, Nicole
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution exposure and respiratory function. This study assesses the role of SES either as confounder or effect modifier of the association between ambient air pollution and lung function. Cross-sectional data from three European multicenter adult cohorts were pooled to assess factors associated with lung function, including annual means of home outdoor NO2. Pre-bronchodilator lung function was measured according to the ATS-criteria. Multiple mixed linear models with random intercepts for study areas were used. Three different factors (education, occupation and neighborhood unemployment rate) were considered to represent SES. NO2 exposure was negatively associated with lung function. Occupation and neighborhood unemployment rates were not associated with lung function. However, the inclusion of the SES-variable education improved the models and the air pollution-lung function associations got slightly stronger. NO2 associations with lung function were not substantially modified by SES-variables. In this multicenter European study we could show that SES plays a role as a confounder in the association of ambient NO2 exposure with lung function.
AB - Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution exposure and respiratory function. This study assesses the role of SES either as confounder or effect modifier of the association between ambient air pollution and lung function. Cross-sectional data from three European multicenter adult cohorts were pooled to assess factors associated with lung function, including annual means of home outdoor NO2. Pre-bronchodilator lung function was measured according to the ATS-criteria. Multiple mixed linear models with random intercepts for study areas were used. Three different factors (education, occupation and neighborhood unemployment rate) were considered to represent SES. NO2 exposure was negatively associated with lung function. Occupation and neighborhood unemployment rates were not associated with lung function. However, the inclusion of the SES-variable education improved the models and the air pollution-lung function associations got slightly stronger. NO2 associations with lung function were not substantially modified by SES-variables. In this multicenter European study we could show that SES plays a role as a confounder in the association of ambient NO2 exposure with lung function.
KW - Air pollution
KW - Environmental equality
KW - Europe
KW - Lung function
KW - Socioeconomic position
UR - http://www.scopus.com/inward/record.url?scp=85067315564&partnerID=8YFLogxK
U2 - 10.3390/ijerph16111901
DO - 10.3390/ijerph16111901
M3 - Article (Academic Journal)
C2 - 31146441
AN - SCOPUS:85067315564
VL - 16
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
SN - 1661-7827
IS - 11
M1 - 1901
ER -