Palladium(II)-catalysed allylic acetate transposition, when driven by the diphenylphosphinoyl (Ph2PO) group, is regiospecific (acetate moves away from the Ph2PO group), stereoselective (the new double bond is E), and stereospecific (the acetate moves suprafacially across the allyl system). The rearranged acetates can be hydrolysed to δ-hydroxy allylic phosphine oxides which are useful intermediates in a variety of synthetic methods.
|Number of pages||11|
|Journal||Journal of the Chemical Society, Perkin Transactions 1|
|Publication status||Published - 1 Dec 1993|