Therapist-delivered internet psychotherapy for depression in primary care: a randomised controlled trial

D Kessler, G Lewis, S Kaur, NJ Wiles, M King, S Welch, D Sharp, R Araya, S Hollinghurst, TJ Peters

Research output: Contribution to journalArticle (Academic Journal)

230 Citations (Scopus)


BACKGROUND: Despite strong evidence for its effectiveness, cognitive-behavioural therapy (CBT) remains difficult to access. Computerised programs have been developed to improve accessibility, but whether these interventions are responsive to individual needs is unknown. We investigated the effectiveness of CBT delivered online in real time by a therapist for patients with depression in primary care. METHODS: In this multicentre, randomised controlled trial, 297 individuals with a score of 14 or more on the Beck depression inventory (BDI) and a confirmed diagnosis of depression were recruited from 55 general practices in Bristol, London, and Warwickshire, UK. Participants were randomly assigned, by a computer-generated code, to online CBT in addition to usual care (intervention; n=149) or to usual care from their general practitioner while on an 8-month waiting list for online CBT (control; n=148). Participants, researchers involved in recruitment, and therapists were masked in advance to allocation. The primary outcome was recovery from depression (BDI score
Original languageEnglish
Pages (from-to)628 - 634
Issue number9690
Publication statusPublished - 22 Aug 2009

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