Skip to content

Timing of menarche and self-harm in adolescence and adulthood: a population-based cohort study

Research output: Contribution to journalArticle

Original languageEnglish
Number of pages9
JournalPsychological Medicine
DOIs
DateAccepted/In press - 25 Jul 2019

Abstract

Background: Previous studies of pubertal timing and self-harm are limited by subjective measures of pubertal timing or by the conflation of self-harm with suicide attempts and ideation. The current study investigates the association between an objective measure of pubertal timing in females – age at menarche – and self-harm with and without suicidal intent in adolescence and adulthood. Method: Birth cohort study based on 4,042 females from the Avon Longitudinal Study of Parents and Children (ALSPAC). Age at menarche was assessed prospectively between ages 8 and 17 years. Lifetime history of self-harm was self-reported at ages 16 and 21 years. Associations between age at menarche and self-harm, both with and without suicidal intent, were examined using multivariable logistic regression. Results: Later age at menarche was associated with a lower risk of lifetime self-harm at age 16 years (OR per year increase in age at menarche 0.87; 95% CI 0.80, 0.95). Compared with normative timing, early menarche (<11.5 years) was associated with an increased risk of self-harm (OR 1.31; 95% CI 1.04, 1.64) and later menarche (> 13.8 years) with a reduced risk (OR 0.74; 95% CI 0.58, 0.93). The pattern of association was similar at age 21 years (OR per year increase in age at menarche 0.92, 95% CI 0.85, 1.00). There was no strong evidence for a difference in associations with suicidal versus non-suicidal self-harm. Conclusions: Risk of self-harm is higher in females with early menarche onset. Future research is needed to establish whether this association is causal and to identify potential mechanisms.

    Structured keywords

  • ALSPAC

    Research areas

  • Self-harm, Menarche, Puberty, ALSPAC

Download statistics

No data available

Documents

Documents

  • Full-text PDF (final published version)

    Rights statement: This is the final published version of the article (version of record). It first appeared online via Cambridge University Press at https://www.cambridge.org/core/journals/psychological-medicine/article/timing-of-menarche-and-selfharm-in-adolescence-and-adulthood-a-populationbased-cohort-study/CCB057306EBF54F73691E2CE99BEDE3A . Please refer to any applicable terms of use of the publisher.

    Final published version, 212 KB, PDF document

    Licence: CC BY

DOI

View research connections

Related faculties, schools or groups