Trajectories of child free sugars intake and dental caries - a population-based birth cohort study

Diep Ha; Huy Nguyen; Lucinda Bell; Gemma  Devenish-Coleman; Rebecca Golley; Murray  Thomson; David  Manton; Sam D Leary; Jane Scott; A John Spencer; Loc G Do

doi:10.1016/j.jdent.2023.104559

Trajectories of child free sugars intake and dental caries - a population-based birth cohort study

Diep Ha^*
, Huy Nguyen
, Lucinda Bell
, Gemma Devenish-Coleman
, Rebecca Golley
, Murray Thomson
, David Manton
, Sam D Leary
, Jane Scott
, A John Spencer
, Loc G Do

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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54 Downloads (Pure)

Abstract

Highlights

•A sustained, high trajectory of FSI from a young age was positively associated with dental caries.

•Consuming high levels of free sugars continuously during the first five years of life contributed a quarter of dental caries cases.

•Study results suggest that measures to minimise FSI must commence in early life.

Abstract

Objectives
To investigate the association between trajectories of free sugars intake during the first five years of life and dental caries experience at five years.

Methods
Data from the SMILE population-based prospective birth cohort study, collected at one, two and five years old, were used. A 3-days dietary diary and food frequency questionnaire were used to estimate free sugars intake (FSI) in grams. The primary outcomes were dental caries prevalence and experience (dmfs). The Group-Based Trajectory Modelling method was used to characterize three FSI trajectories (‘Low and increasing’; ‘Moderate and increasing’; and ‘High and increasing’), which were the main exposures. Multivariable regression models were generated to compute adjusted prevalence ratios (APR) and rate ratios (ARR) for the exposure, controlling for socioeconomic factors.

Results
The prevalence of caries was 23.3%, with a mean dmfs of 1.4, and a median of 3.0 among those who had caries. There were clear gradients of caries prevalence and experience by the FSI trajectories. The ‘High and increasing’ had an APR of 2.13 (95%CI 1.23-3.70) and ARR of 2.77 (95%CI 1.45-5.32) against the ‘Low and increasing’. The ‘Moderate and increasing’ group had intermediate estimates. A quarter of the caries cases could have been prevented if the whole study sample had been in the ‘Low and increasing’ FSI trajectory.

Conclusion
A sustained, high trajectory of FSI from a young age was positively associated with child dental caries. Measures to minimise consumption of free sugars must commence early in life.

Clinical significance
The study has provided high level evidence to inform clinicians’ decisions in promoting a healthy dietary pattern for young children.

Original language	English
Article number	104559
Number of pages	24
Journal	Journal of Dentistry
Volume	134
Early online date	23 May 2023
DOIs	https://doi.org/10.1016/j.jdent.2023.104559
Publication status	Published - 1 Jul 2023

Bibliographical note

Funding Information:
The SMILE birth cohort is funded by Australian National Health and Medical Research Council Project Grants # APP1046219 2013-17 and APP144595 2018-22 .

Publisher Copyright:
© 2023

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@article{f1ad796e6b094b1ca5b72d4bb152e0db,

title = "Trajectories of child free sugars intake and dental caries - a population-based birth cohort study",

abstract = "Highlights •A sustained, high trajectory of FSI from a young age was positively associated with dental caries. •Consuming high levels of free sugars continuously during the first five years of life contributed a quarter of dental caries cases. •Study results suggest that measures to minimise FSI must commence in early life. Abstract Objectives To investigate the association between trajectories of free sugars intake during the first five years of life and dental caries experience at five years. Methods Data from the SMILE population-based prospective birth cohort study, collected at one, two and five years old, were used. A 3-days dietary diary and food frequency questionnaire were used to estimate free sugars intake (FSI) in grams. The primary outcomes were dental caries prevalence and experience (dmfs). The Group-Based Trajectory Modelling method was used to characterize three FSI trajectories ({\textquoteleft}Low and increasing{\textquoteright}; {\textquoteleft}Moderate and increasing{\textquoteright}; and {\textquoteleft}High and increasing{\textquoteright}), which were the main exposures. Multivariable regression models were generated to compute adjusted prevalence ratios (APR) and rate ratios (ARR) for the exposure, controlling for socioeconomic factors. Results The prevalence of caries was 23.3\%, with a mean dmfs of 1.4, and a median of 3.0 among those who had caries. There were clear gradients of caries prevalence and experience by the FSI trajectories. The {\textquoteleft}High and increasing{\textquoteright} had an APR of 2.13 (95\%CI 1.23-3.70) and ARR of 2.77 (95\%CI 1.45-5.32) against the {\textquoteleft}Low and increasing{\textquoteright}. The {\textquoteleft}Moderate and increasing{\textquoteright} group had intermediate estimates. A quarter of the caries cases could have been prevented if the whole study sample had been in the {\textquoteleft}Low and increasing{\textquoteright} FSI trajectory. Conclusion A sustained, high trajectory of FSI from a young age was positively associated with child dental caries. Measures to minimise consumption of free sugars must commence early in life. Clinical significance The study has provided high level evidence to inform clinicians{\textquoteright} decisions in promoting a healthy dietary pattern for young children.",

author = "Diep Ha and Huy Nguyen and Lucinda Bell and Gemma Devenish-Coleman and Rebecca Golley and Murray Thomson and David Manton and Leary, \{Sam D\} and Jane Scott and Spencer, \{A John\} and Do, \{Loc G\}",

note = "Funding Information: The SMILE birth cohort is funded by Australian National Health and Medical Research Council Project Grants \# APP1046219 2013-17 and APP144595 2018-22 . Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = jul,

day = "1",

doi = "10.1016/j.jdent.2023.104559",

language = "English",

volume = "134",

journal = "Journal of Dentistry",

issn = "0300-5712",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Trajectories of child free sugars intake and dental caries - a population-based birth cohort study

AU - Ha, Diep

AU - Nguyen, Huy

AU - Bell, Lucinda

AU - Devenish-Coleman, Gemma

AU - Golley, Rebecca

AU - Thomson, Murray

AU - Manton, David

AU - Leary, Sam D

AU - Scott, Jane

AU - Spencer, A John

AU - Do, Loc G

N1 - Funding Information: The SMILE birth cohort is funded by Australian National Health and Medical Research Council Project Grants # APP1046219 2013-17 and APP144595 2018-22 . Publisher Copyright: © 2023

PY - 2023/7/1

Y1 - 2023/7/1

N2 - Highlights •A sustained, high trajectory of FSI from a young age was positively associated with dental caries. •Consuming high levels of free sugars continuously during the first five years of life contributed a quarter of dental caries cases. •Study results suggest that measures to minimise FSI must commence in early life. Abstract Objectives To investigate the association between trajectories of free sugars intake during the first five years of life and dental caries experience at five years. Methods Data from the SMILE population-based prospective birth cohort study, collected at one, two and five years old, were used. A 3-days dietary diary and food frequency questionnaire were used to estimate free sugars intake (FSI) in grams. The primary outcomes were dental caries prevalence and experience (dmfs). The Group-Based Trajectory Modelling method was used to characterize three FSI trajectories (‘Low and increasing’; ‘Moderate and increasing’; and ‘High and increasing’), which were the main exposures. Multivariable regression models were generated to compute adjusted prevalence ratios (APR) and rate ratios (ARR) for the exposure, controlling for socioeconomic factors. Results The prevalence of caries was 23.3%, with a mean dmfs of 1.4, and a median of 3.0 among those who had caries. There were clear gradients of caries prevalence and experience by the FSI trajectories. The ‘High and increasing’ had an APR of 2.13 (95%CI 1.23-3.70) and ARR of 2.77 (95%CI 1.45-5.32) against the ‘Low and increasing’. The ‘Moderate and increasing’ group had intermediate estimates. A quarter of the caries cases could have been prevented if the whole study sample had been in the ‘Low and increasing’ FSI trajectory. Conclusion A sustained, high trajectory of FSI from a young age was positively associated with child dental caries. Measures to minimise consumption of free sugars must commence early in life. Clinical significance The study has provided high level evidence to inform clinicians’ decisions in promoting a healthy dietary pattern for young children.

AB - Highlights •A sustained, high trajectory of FSI from a young age was positively associated with dental caries. •Consuming high levels of free sugars continuously during the first five years of life contributed a quarter of dental caries cases. •Study results suggest that measures to minimise FSI must commence in early life. Abstract Objectives To investigate the association between trajectories of free sugars intake during the first five years of life and dental caries experience at five years. Methods Data from the SMILE population-based prospective birth cohort study, collected at one, two and five years old, were used. A 3-days dietary diary and food frequency questionnaire were used to estimate free sugars intake (FSI) in grams. The primary outcomes were dental caries prevalence and experience (dmfs). The Group-Based Trajectory Modelling method was used to characterize three FSI trajectories (‘Low and increasing’; ‘Moderate and increasing’; and ‘High and increasing’), which were the main exposures. Multivariable regression models were generated to compute adjusted prevalence ratios (APR) and rate ratios (ARR) for the exposure, controlling for socioeconomic factors. Results The prevalence of caries was 23.3%, with a mean dmfs of 1.4, and a median of 3.0 among those who had caries. There were clear gradients of caries prevalence and experience by the FSI trajectories. The ‘High and increasing’ had an APR of 2.13 (95%CI 1.23-3.70) and ARR of 2.77 (95%CI 1.45-5.32) against the ‘Low and increasing’. The ‘Moderate and increasing’ group had intermediate estimates. A quarter of the caries cases could have been prevented if the whole study sample had been in the ‘Low and increasing’ FSI trajectory. Conclusion A sustained, high trajectory of FSI from a young age was positively associated with child dental caries. Measures to minimise consumption of free sugars must commence early in life. Clinical significance The study has provided high level evidence to inform clinicians’ decisions in promoting a healthy dietary pattern for young children.

U2 - 10.1016/j.jdent.2023.104559

DO - 10.1016/j.jdent.2023.104559

M3 - Article (Academic Journal)

C2 - 37230240

SN - 0300-5712

VL - 134

JO - Journal of Dentistry

JF - Journal of Dentistry

M1 - 104559

ER -

Trajectories of child free sugars intake and dental caries - a population-based birth cohort study

Abstract

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