Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.

H Lu; WM Wagner; E Gad; Y Yang; H Duan; LM Amon; Denend N Van; ER Larson; A Chang; H Tufvesson; ML Disis

doi:10.4049/jimmunol.0902997

Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.

H Lu
, WM Wagner
, E Gad
, Y Yang
, H Duan
, LM Amon
, Denend N Van
, ER Larson
, A Chang
, H Tufvesson
, ML Disis

School of Biological Sciences

Research output: Contribution to journal › Article (Academic Journal) › peer-review

75 Citations (Scopus)

Original language	English
Journal	Journal of Immunology
DOIs	https://doi.org/10.4049/jimmunol.0902997
Publication status	Published - May 2010

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@article{d84edf371ef3471ab919019df0847b02,

title = "Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.",

author = "H Lu and WM Wagner and E Gad and Y Yang and H Duan and LM Amon and Van, \{Denend N\} and ER Larson and A Chang and H Tufvesson and ML Disis",

year = "2010",

month = may,

doi = "10.4049/jimmunol.0902997",

language = "English",

journal = "Journal of Immunology",

issn = "0022-1767",

publisher = "American Association of Immunologists",

}

TY - JOUR

T1 - Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.

AU - Lu, H

AU - Wagner, WM

AU - Gad, E

AU - Yang, Y

AU - Duan, H

AU - Amon, LM

AU - Van, Denend N

AU - Larson, ER

AU - Chang, A

AU - Tufvesson, H

AU - Disis, ML

PY - 2010/5

Y1 - 2010/5

UR - http://europepmc.org/abstract/med/20308630

U2 - 10.4049/jimmunol.0902997

DO - 10.4049/jimmunol.0902997

M3 - Article (Academic Journal)

C2 - 20308630

SN - 0022-1767

JO - Journal of Immunology

JF - Journal of Immunology

ER -

Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.

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