Treatment of pediatric pulmonary hypertension

Amy Hawkins, Robert Tulloh*

*Corresponding author for this work

Research output: Contribution to journalReview article (Academic Journal)

24 Citations (Scopus)

Abstract

Pulmonary hypertension was once thought to be a rare condition and only managed in specialized centers. Now however, with the advent of echocardiography, it is found in many clinical scenarios, in the neonate with chronic lung disease, in the acute setting in the intensive care unit, in connective tissue disease and in cardiology pre- and postoperatively. We have a better understanding of the pathological process and have a range of medication which is starting to be able to palliate this previously fatal condition. This review describes the areas that are known in this condition and those that are less familiar. The basic physiology behind pulmonary hypertension and pulmonary vascular disease is explained. The histopathologic process and the various diagnostic tools are described and are followed by the current and future therapy at our disposal.

Original languageEnglish
Pages (from-to)509-524
Number of pages16
JournalVascular Health and Risk Management
Volume5
Publication statusPublished - 1 Dec 2009

Keywords

  • Congenital heart disease
  • Pulmonary hypertension
  • Pulmonary vascular resistance
  • Pulmonary vasodilators

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