TY - JOUR
T1 - Tuberculosis and people who use drugs
T2 - why focus on this overlooked population is important and why adapted interventions are necessary
AU - D'Ottavi, Morgana R
AU - Godfrey-Faussett, Peter
AU - Merle, Corinne
AU - Sofonea, Mircea
AU - Laureillard, Didier
AU - Vickerman, Peter T
AU - Molès, Jean-Pierre
AU - Altice, Frederick
AU - Van de Perre, Philippe
AU - Stone, Jack
AU - Nagot, Nicolas
N1 - Publisher Copyright:
© 2025 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license
PY - 2025/1/22
Y1 - 2025/1/22
N2 - People who use drugs (PWUD) are highly affected by tuberculosis in areas where Mycobacterium tuberculosis is endemic. However, this high-risk group is largely neglected in the activities of national TB programmes. The active case-finding, screening and linkage to care strategies designed for the general population are not adapted to the needs of PWUD. PWUD are a stigmatised group who are difficult to reach for TB case finding and prevention. In addition, access to care, linkage to care and treatment adherence are challenging for such a marginalised population. Learning from the HIV field about successful interventions targeting this high-risk group, we advocate for the implementation of TB interventions tailored to PWUD, highlighting the key role that community-based approaches could play in both design and implementation. Finally, in addition to reducing health inequities by reducing the excess TB burden among PWUD, these targeted interventions can also significantly reduce TB transmission at the wider population-level.
AB - People who use drugs (PWUD) are highly affected by tuberculosis in areas where Mycobacterium tuberculosis is endemic. However, this high-risk group is largely neglected in the activities of national TB programmes. The active case-finding, screening and linkage to care strategies designed for the general population are not adapted to the needs of PWUD. PWUD are a stigmatised group who are difficult to reach for TB case finding and prevention. In addition, access to care, linkage to care and treatment adherence are challenging for such a marginalised population. Learning from the HIV field about successful interventions targeting this high-risk group, we advocate for the implementation of TB interventions tailored to PWUD, highlighting the key role that community-based approaches could play in both design and implementation. Finally, in addition to reducing health inequities by reducing the excess TB burden among PWUD, these targeted interventions can also significantly reduce TB transmission at the wider population-level.
U2 - 10.1016/S2214-109X(24)00481-9
DO - 10.1016/S2214-109X(24)00481-9
M3 - Article (Academic Journal)
C2 - 39862874
SN - 2214-109X
VL - 13
SP - e593-e598
JO - Lancet Global Health
JF - Lancet Global Health
IS - 3
ER -
