Tubular nanomaterials for bone tissue engineering

Naomi Akiyama, Kapil d. Patel, Eun jo Jang, Mark r. Shannon, Rajkumar Patel, Madhumita Patel, Adam willis Perriman

Research output: Contribution to journalBook/Film/Article review (Academic Journal)peer-review

20 Citations (Scopus)

Abstract

Nanomaterial composition, morphology, and mechanical performance are critical parameters for tissue engineering. Within this rapidly expanding space, tubular nanomaterials (TNs), including carbon nanotubes (CNTs), titanium oxide nanotubes (TNTs), halloysite nanotubes (HNTs), silica nanotubes (SiNTs), and hydroxyapatite nanotubes (HANTs) have shown significant potential across a broad range of applications due to their high surface area, versatile surface chemistry, well-defined mechanical properties, excellent biocompatibility, and monodispersity. These include drug delivery vectors, imaging contrast agents, and scaffolds for bone tissue engineering. This review is centered on the recent developments in TN-based biomaterials for structural tissue engineering, with a strong focus on bone tissue regeneration. It includes a detailed literature review on TN-based orthopedic coatings for metallic implants and composite scaffolds to enhance in vivo bone regeneration.
Original languageEnglish
Pages (from-to)6225-6248
Number of pages24
JournalJournal of Materials Chemistry B
Volume11
Issue number27
DOIs
Publication statusPublished - 13 Jun 2023

Bibliographical note

Funding Information:
The authors would like to acknowledge the Engineering and Physical Science Research Council (EPSRC), the UK for emPOWER program at University of Bristol under Grant No. EP/T020792/1.

Publisher Copyright:
© 2023 The Royal Society of Chemistry.

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