Two-stage meta-analysis of survival data from individual participants using percentile ratios

Jessica K Barrett, Vern T Farewell, Fotios Siannis, Jayne Tierney, Julian P T Higgins

Research output: Contribution to journalArticle (Academic Journal)peer-review

10 Citations (Scopus)

Abstract

Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030-3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a novel two-stage method for the meta-analysis of percentile ratios that avoids distributional assumptions at the study level.
Original languageEnglish
Pages (from-to)4296-308
Number of pages13
JournalStatistics in Medicine
Volume31
Issue number30
DOIs
Publication statusPublished - 2012

Bibliographical note

Copyright © 2012 John Wiley & Sons, Ltd.

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