UK Renal Registry 18th Annual Report: Chapter 10 Clinical, Haematological and Biochemical Parameters in Patients Receiving Renal Replacement Therapy in Paediatric Centres in the UK in 2014: National and Centre-specific Analyses

Alexander J Hamilton, Fiona E M Braddon, Anna Casula, Carol Inward, Malcolm Lewis, Tamara Mallett, Heather Maxwell, Catherine O’ Brien, Yincent Tse, Manish D Sinha

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Abstract

* The median height z-score for paediatric patients on dialysis was −2.1 and for those with a functioning transplant −1.3. Children transplanted before the age of 12 years improved their height z-score over the subsequent five years, whereas those older than 12 maintained their height z-score, with all transplanted patients having a similar median height z-score after five years of starting renal
replacement therapy (RRT).

* The median weight z-score for children on dialysis was −1.4 whereas children with a functioning transplant had a near normal weight for age and sex with
a median z-score of −0.3.

* Of those with data, 75% of the prevalent paediatric RRT population had one or more ‘traditional’ risk factors for cardiovascular disease, with 1 in 10 having all three risk factors present.

* For the 10 centres reporting quarterly laboratory data, the average creatinine in transplant patients was 79 μmol/L; dialysis patients had normal average anaemia and acidosis markers and evidence of secondary hyperparathyroidism with an average PTH of 17.3 pmol/L.

* For transplant patients, 80% achieved the systolic blood pressure (SBP) standard and 93% achieved the haemoglobin standard.

* For haemodialysis patients, 57% achieved the SBP standard, 62% achieved the haemoglobin standard, 82% achieved the calcium standard, 51% achieved the phosphate standard and 39% achieved the parathyroid hormone (PTH) standard.

* For peritoneal dialysis patients, 70% achieved the SBP standard, 77% achieved the haemoglobin standard, 72% achieved the calcium standard, 54% achieved the phosphate standard and 33% achieved the PTH standard.
Original languageEnglish
Pages (from-to)237-251
Number of pages15
JournalNephron
Volume132 Suppl 1
DOIs
Publication statusPublished - 19 Apr 2016

Keywords

  • Adolescents
  • Biochemical variables
  • Blood pressure
  • BMI
  • Children
  • Dialysis
  • Established renal failure
  • Growth
  • Haemoglobin
  • Height
  • Hypertension
  • Paediatric
  • Quality improvement
  • Renal replacement therapy
  • Transplant
  • Weight
  • Young adults

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