Ulceration of the lower leg after total knee replacement a five-year review

S D Muller, F M Khaw, R Morris, A E Crozier, P J Gregg

Research output: Contribution to journalArticle (Academic Journal)peer-review

11 Citations (Scopus)


Ulceration of the lower leg is considered to be a hard' clinical endpoint of venous thrombosis. Total knee replacement (TKR) is a significant risk factor for venous thrombosis of the leg and therefore potentially for ulceration. We sent a postal questionnaire to 244 patients at a minimum of five years after TKR enquiring about the development of ulceration since their TKR. The overall incidence of ulceration, both active and healed, was 8.67% which is similar to that in the age-matched general population (9.6% to 12.6%), as was the prevalence of active ulceration. We also identified no clear association between venographically-confirmed postoperative deep-venous thrombosis (DVT) and the incidence and prevalence of ulcers at five years. We suggest that after TKR DVT is not a significant risk factor for ulceration of the leg and that perioperative chemical thromboprophylaxis may not be justified on these grounds.

Original languageEnglish
Pages (from-to)1116-8
Number of pages3
JournalJournal of Bone and Joint Surgery
Issue number8
Publication statusPublished - Nov 2001


  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Knee
  • Humans
  • Leg Ulcer
  • Middle Aged
  • Postoperative Complications
  • Venous Thrombosis

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