Urinary tract infection in patients with acute non-gonococcal urethritis

Andrew Leung, Shaw Taylor, Angela Smith, Robert Spencer, Paddy Horner

Research output: Contribution to journalArticle (Academic Journal)peer-review

15 Citations (Scopus)


In young sexually active male patients, clinical differentiation between non-gonococcal urethritis (NGU) and urinary tract infection (UTI) can be difficult. UTI as a cause of NGU has been suggested before, but the prevalence of UTI among acute NGU patients has not been evaluated. We conducted a prospective cross-sectional study of 156 male patients with clinical features of acute urethritis. The prevalence of UTI among acute NGU patients was 6.4% (CI: 1.5-11.3%). There was a possible association between UTI and NGU but this was not statistically significant. The sensitivity and specificity for combining leucocyte esterase and nitrite tests were 83.3% and 89.8%, respectively, with a negative predictive value of 98.8%. We conclude that a mid-stream urine specimen should routinely be collected in patients with symptoms of urethritis. This should be analysed by dipsticks incorporating nitrite and leucocyte esterase tests. Those with a positive dipstick should then be confirmed by culture.

Original languageEnglish
Pages (from-to)801-4
Number of pages4
JournalInternational Journal of STD and AIDS
Issue number12
Publication statusPublished - Dec 2002


  • Acute Disease
  • Carboxylic Ester Hydrolases
  • Chlamydia Infections
  • Chlamydia trachomatis
  • Cross-Sectional Studies
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Male
  • Nitrites
  • Prevalence
  • Prospective Studies
  • Reagent Strips
  • Sensitivity and Specificity
  • United Kingdom
  • Urethritis
  • Urinary Tract Infections
  • Journal Article


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