Abstract
Objective: The purpose of this study is to report the use of ILE in dogs presenting with suspected tremorgenic mycotoxicosis based on signs of intoxication and known ingestion of mouldy food or compost.
Background: Intralipid emulsion therapy (ILE) is being used for toxicoses associated with fat soluble agents. As tremorgenic mycotoxins are lipophilic in nature, the use of ILE may be of benefit in these patients.
Methods: Medical records of all dogs examined at any Vets Now clinic between November 2012 and November 2016, in which ILE had been used, were reviewed and 53 cases were included in the study.
Results: In 96% cases there was clinical improvement recorded post ILE administration within a median time of 4 hours. No adverse effects were seen during the infusion or up to the time of discharge.
Conclusion: The administration of ILE seems to be associated with a beneficial effect in the short term in this population of animals. Prospective evaluation of this therapy is warranted to further evaluate the use of ILE in these cases.
Background: Intralipid emulsion therapy (ILE) is being used for toxicoses associated with fat soluble agents. As tremorgenic mycotoxins are lipophilic in nature, the use of ILE may be of benefit in these patients.
Methods: Medical records of all dogs examined at any Vets Now clinic between November 2012 and November 2016, in which ILE had been used, were reviewed and 53 cases were included in the study.
Results: In 96% cases there was clinical improvement recorded post ILE administration within a median time of 4 hours. No adverse effects were seen during the infusion or up to the time of discharge.
Conclusion: The administration of ILE seems to be associated with a beneficial effect in the short term in this population of animals. Prospective evaluation of this therapy is warranted to further evaluate the use of ILE in these cases.
| Original language | English |
|---|---|
| Article number | 166 |
| Pages (from-to) | 1-8 |
| Number of pages | 8 |
| Journal | Veterinary Evidence |
| Volume | 3 |
| Issue number | 2 |
| Early online date | 24 May 2018 |
| DOIs | |
| Publication status | Published - 2018 |
Keywords
- intralipid
- mycotoxicosis
- dogs
- ILE