Skip to content

Using SITAR (SuperImposition by Translation and Rotation) to estimate age at peak height velocity in Avon Longitudinal Study of Parents and Children

Research output: Contribution to journalArticle

Original languageEnglish
Article number90
Number of pages10
JournalWellcome Open Research
Volume3
DOIs
DateAccepted/In press - 20 Jul 2018
DatePublished (current) - 3 Oct 2018

Abstract

Puberty is a time of substantial biological and psychological changes. One of the hallmarks of puberty is a rapid growth spurt, however its timing varies between individuals. The impact of pubertal timing on later health outcomes has been of interest in life course epidemiology, however its measurement can be challenging. Age at peak height velocity (aPHV) offers an objective measure of pubertal timing without having to rely on physical examination or self-report. We describe the derivation of aPHV estimates in Avon Longitudinal Study of Parents and Children (ALSPAC) offspring, using Superimposition by Translation And Rotation (SITAR) mixed effects growth curve analysis. ALSPAC is a rich source of phenotypic and genotypic data and given the importance of pubertal timing for later health outcomes, these data offer an opportunity to explore the determinants and consequences of aPHV.

    Research areas

  • ALSPAC, Age at peak height velocity, pubertal timing, growth

Download statistics

No data available

Documents

Documents

  • Full-text PDF (final published version)

    Rights statement: This is the final published version of the article (version of record). It first appeared online via Wellcome Trust at https://wellcomeopenresearch.org/articles/3-90/v1 . Please refer to any applicable terms of use of the publisher.

    Final published version, 559 KB, PDF document

    Licence: CC BY

DOI

View research connections

Related faculties, schools or groups