Using the Person-Based Approach to optimise a digital intervention for the management of hypertension

Katherine Bradbury, Katherine Morton, Rebecca Band, Anne van Woezik, Rebecca Grist, Richard J McManus, Paul Little, Lucy Yardley

Research output: Contribution to journalArticle (Academic Journal)peer-review

39 Citations (Scopus)
228 Downloads (Pure)


BACKGROUND: For behaviour-change interventions to be successful they must be acceptable to users and overcome barriers to behaviour change. The Person-Based Approach can help to optimise interventions to maximise acceptability and engagement. This article presents a novel, efficient and systematic method that can be used as part of the Person-Based Approach to rapidly analyse data from development studies to inform intervention modifications. We describe how we used this approach to optimise a digital intervention for patients with hypertension (HOME BP), which aims to implement medication and lifestyle changes to optimise blood pressure control.

METHODS: In study 1, hypertensive patients (N = 12) each participated in three think-aloud interviews, providing feedback on a prototype of HOME BP. In study 2 patients (N = 11) used HOME BP for three weeks and were then interviewed about their experiences. Studies 1 and 2 were used to identify detailed changes to the intervention content and potential barriers to engagement with HOME BP. In study 3 (N = 7) we interviewed hypertensive patients who were not interested in using an intervention like HOME BP to identify potential barriers to uptake, which informed modifications to our recruitment materials. Analysis in all three studies involved detailed tabulation of patient data and comparison to our modification criteria.

RESULTS: Studies 1 and 2 indicated that the HOME BP procedures were generally viewed as acceptable and feasible, but also highlighted concerns about monitoring blood pressure correctly at home and making medication changes remotely. Patients in study 3 had additional concerns about the safety and security of the intervention. Modifications improved the acceptability of the intervention and recruitment materials.

CONCLUSIONS: This paper provides a detailed illustration of how to use the Person-Based Approach to refine a digital intervention for hypertension. The novel, efficient approach to analysis and criteria for deciding when to implement intervention modifications described here may be useful to others developing interventions.

Original languageEnglish
Article numbere0196868
Number of pages18
JournalPLoS ONE
Issue number5
Publication statusPublished - 3 May 2018

Structured keywords

  • Digital Health
  • Physical and Mental Health


  • Adult
  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents/therapeutic use
  • Blood Pressure
  • Blood Pressure Determination
  • Blood Pressure Monitoring, Ambulatory/methods
  • Disease Management
  • Female
  • Humans
  • Hypertension/drug therapy
  • Male
  • Middle Aged
  • Self Care/psychology
  • Surveys and Questionnaires
  • Telemedicine/methods
  • United Kingdom


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