Validation of conversion between Mini-Mental State Examination and Montreal Cognitive Assessment

Michael A Lawton; Meike Kasten; Margaret T May; Brit Mollenhauer; Martina Schaumburg; Inga Liepelt-Scarfone; Walter Maetzler; Eva-Juliane Vollstedt; Michele Hu; Daniela Berg; Yoav Ben-Shlomo

doi:10.1002/mds.26498

Validation of conversion between Mini-Mental State Examination and Montreal Cognitive Assessment

Michael A Lawton, Meike Kasten, Margaret T May, Brit Mollenhauer, Martina Schaumburg, Inga Liepelt-Scarfone, Walter Maetzler, Eva-Juliane Vollstedt, Michele Hu, Daniela Berg, Yoav Ben-Shlomo

Bristol Medical School (PHS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

25 Citations (Scopus)

551 Downloads (Pure)

Abstract

Background
Harmonising data across cohorts is important for validating findings or combining data in meta-analyses. We replicate and validate a previous conversion of Montreal Cognitive Assessment (MOCA) to Mini-Mental State Examination (MMSE) in Parkinson’s disease (PD).

Methods
We used 5 studies with 1,161 PD individuals and 2,091 observations measured with both the MOCA and MMSE. We compared a previously published conversion table using equipercentile equating with log-linear smoothing to our internally derived scores.

Results
Both conversions found good agreement within and across the studies when comparing true and converted MMSE (mean difference 0.05 (SD 1.84) median difference 0; inter-quartile range -1 to 1, using internal conversion).

Conclusion
These results show that one can get a reliable and valid conversion between two commonly used measures of cognition in PD studies. These approaches need to be applied to other scales and domains to enable large scale collaborative analyses across multiple PD cohorts.

Original language	English
Pages (from-to)	593-596
Number of pages	4
Journal	Movement Disorders
Volume	31
Issue number	4
Early online date	10 Feb 2016
DOIs	https://doi.org/10.1002/mds.26498
Publication status	Published - Apr 2016

Keywords

Parkinson's disease
Mini–Mental State Examination
Montreal Cognitive Assessment
equating

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10.1002/mds.26498

Lawton_et_al-2016-Movement_Disorders
© 2016 The Authors. International Parkinson and Movement Disorder Society This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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Lawton, Michael A ; Kasten, Meike ; May, Margaret T ; Mollenhauer, Brit ; Schaumburg, Martina ; Liepelt-Scarfone, Inga ; Maetzler, Walter ; Vollstedt, Eva-Juliane ; Hu, Michele ; Berg, Daniela ; Ben-Shlomo, Yoav. / Validation of conversion between Mini-Mental State Examination and Montreal Cognitive Assessment. In: Movement Disorders. 2016 ; Vol. 31, No. 4. pp. 593-596.

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title = "Validation of conversion between Mini-Mental State Examination and Montreal Cognitive Assessment",

abstract = "BackgroundHarmonising data across cohorts is important for validating findings or combining data in meta-analyses. We replicate and validate a previous conversion of Montreal Cognitive Assessment (MOCA) to Mini-Mental State Examination (MMSE) in Parkinson{\textquoteright}s disease (PD). MethodsWe used 5 studies with 1,161 PD individuals and 2,091 observations measured with both the MOCA and MMSE. We compared a previously published conversion table using equipercentile equating with log-linear smoothing to our internally derived scores. ResultsBoth conversions found good agreement within and across the studies when comparing true and converted MMSE (mean difference 0.05 (SD 1.84) median difference 0; inter-quartile range -1 to 1, using internal conversion). ConclusionThese results show that one can get a reliable and valid conversion between two commonly used measures of cognition in PD studies. These approaches need to be applied to other scales and domains to enable large scale collaborative analyses across multiple PD cohorts.",

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Validation of conversion between Mini-Mental State Examination and Montreal Cognitive Assessment. / Lawton, Michael A; Kasten, Meike; May, Margaret T; Mollenhauer, Brit; Schaumburg, Martina; Liepelt-Scarfone, Inga; Maetzler, Walter; Vollstedt, Eva-Juliane; Hu, Michele; Berg, Daniela; Ben-Shlomo, Yoav.

In: Movement Disorders, Vol. 31, No. 4, 04.2016, p. 593-596.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Validation of conversion between Mini-Mental State Examination and Montreal Cognitive Assessment

AU - Lawton, Michael A

AU - Kasten, Meike

AU - May, Margaret T

AU - Mollenhauer, Brit

AU - Schaumburg, Martina

AU - Liepelt-Scarfone, Inga

AU - Maetzler, Walter

AU - Vollstedt, Eva-Juliane

AU - Hu, Michele

AU - Berg, Daniela

AU - Ben-Shlomo, Yoav

PY - 2016/4

Y1 - 2016/4

N2 - BackgroundHarmonising data across cohorts is important for validating findings or combining data in meta-analyses. We replicate and validate a previous conversion of Montreal Cognitive Assessment (MOCA) to Mini-Mental State Examination (MMSE) in Parkinson’s disease (PD). MethodsWe used 5 studies with 1,161 PD individuals and 2,091 observations measured with both the MOCA and MMSE. We compared a previously published conversion table using equipercentile equating with log-linear smoothing to our internally derived scores. ResultsBoth conversions found good agreement within and across the studies when comparing true and converted MMSE (mean difference 0.05 (SD 1.84) median difference 0; inter-quartile range -1 to 1, using internal conversion). ConclusionThese results show that one can get a reliable and valid conversion between two commonly used measures of cognition in PD studies. These approaches need to be applied to other scales and domains to enable large scale collaborative analyses across multiple PD cohorts.

AB - BackgroundHarmonising data across cohorts is important for validating findings or combining data in meta-analyses. We replicate and validate a previous conversion of Montreal Cognitive Assessment (MOCA) to Mini-Mental State Examination (MMSE) in Parkinson’s disease (PD). MethodsWe used 5 studies with 1,161 PD individuals and 2,091 observations measured with both the MOCA and MMSE. We compared a previously published conversion table using equipercentile equating with log-linear smoothing to our internally derived scores. ResultsBoth conversions found good agreement within and across the studies when comparing true and converted MMSE (mean difference 0.05 (SD 1.84) median difference 0; inter-quartile range -1 to 1, using internal conversion). ConclusionThese results show that one can get a reliable and valid conversion between two commonly used measures of cognition in PD studies. These approaches need to be applied to other scales and domains to enable large scale collaborative analyses across multiple PD cohorts.

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KW - Montreal Cognitive Assessment

KW - equating

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