Vasopressin and oxytocin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Daniel Bichet, Michel Bouvier, Bice Chini, Gerald Gimpi, Giles Guillon, Tadashi Kimura, Mark Knepper, Stephen J Lolait, Maurice Manning, Bernard Mouillac, Anne-Marie O'Carroll, Claudine Serradeil-Le Gal, Melvyn Soloff, Joseph Verbalis, Mark Wheatlry, Hans Zingg

Research output: Contribution to journalArticle (Academic Journal)peer-review

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Abstract

Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [92]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [67].
Original languageEnglish
Number of pages19
JournalIUPHAR/BPS Guide to PHarmacology CITE
Volume2019
Issue number4
DOIs
Publication statusPublished - 16 Sep 2019

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