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Vasopressin and oxytocin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  • Daniel Bichet
  • , Michel Bouvier
  • , Bice Chini
  • , Gerald Gimpi
  • , Giles Guillon
  • , Tadashi Kimura
  • , Mark Knepper
  • , Stephen J Lolait
  • , Maurice Manning
  • , Bernard Mouillac
  • , Anne-Marie O'Carroll
  • , Claudine Serradeil-Le Gal
  • , Melvyn Soloff
  • , Joseph Verbalis
  • , Mark Wheatlry
  • , Hans Zingg

Research output: Contribution to journalArticle (Academic Journal)peer-review

131 Downloads (Pure)

Abstract

Vasopressin (AVP) and oxytocin (OT) receptors (nomenclature as recommended by NC-IUPHAR [92]) are activated by the endogenous cyclic nonapeptides vasopressin and oxytocin. These peptides are derived from precursors which also produce neurophysins (neurophysin I for oxytocin; neurophysin II for vasopressin). Vasopressin and oxytocin differ at only 2 amino acids (positions 3 and 8). There are metabolites of these neuropeptides that may be biologically active [67].
Original languageEnglish
Number of pages19
JournalIUPHAR/BPS Guide to PHarmacology CITE
Volume2019
Issue number4
DOIs
Publication statusPublished - 16 Sept 2019

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