Visible light photocatalytic decarboxylative monofluoroalkenylation of α-amino acids with gem-difluoroalkenes

Jingjing Li, Quentin Lefebvre, Haijun Yang, Yufen Zhao, Hua Fu

Research output: Contribution to journalArticle (Academic Journal)

40 Citations (Scopus)
241 Downloads (Pure)

Abstract

α-Amino acids are among the most common biologically active molecules in nature, and their functionalization has attracted much attention. In this communication, a novel, efficient and general visible-light photocatalytic decarboxylative monofluoroalkenylation of N-protected α-amino acids with gem-difluoroalkenes is reported, affording the corresponding α-amino monofluoroalkenes which might find applications in medical chemistry and materials science. The reaction proceeded at room temperature with high efficiency and tolerance of various functional groups.

Original languageEnglish
Pages (from-to)10299-10302
Number of pages4
JournalChemical Communications
Volume53
Issue number74
DOIs
Publication statusPublished - 29 Aug 2017

Keywords

  • Journal Article

Fingerprint Dive into the research topics of 'Visible light photocatalytic decarboxylative monofluoroalkenylation of α-amino acids with gem-difluoroalkenes'. Together they form a unique fingerprint.

Cite this